Protein Structure — Function Relationship, Softcover reprint of the original 1st ed. 1996

Although many pursue understanding of the relationship between protein structure and function for the thrill of pure science, the pay-off in a much broader sense is the ability to manipulate the Earth's chemistry and biology to improve the quality of life for mankind. Immediately goals of this area of research include identification of the life-supporting functions of proteins, and the fundamental forces that facilitate these functions. Upon reaching these goals, we shall have the understanding to direct and the tools required to implement changes that will dramatically improve the quality of life. For example, under­ standing the chemical mechanism of diseases will facilitate development of new therapeutic drugs. Likewise, understanding of chemical mechanisms of plant growth will be used with biotechnology to improve food production under adverse climatic conditions. The challenge to understand details of protein structure/function relationships is enormous and requires an international effort for success. To direct the chemistry and biology of our environment in a positive sense will require efforts from bright, imaginative scientists located throughout the world. Although the emergence of FAX, e-mail, and the World Wide Web has revolutionized international communication, there remains a need for scientists located in distant parts of the world to occasionally meet face to face.

How Is the Dioxygeniron Bond Manipulated by Transport and Catalytic Haem Proteins? (M. Akhtar). A New Flow Modulated Continuous Bioreactor Based on Inversed Capillary Membranes for Low Risk Gene Technology (H. Bauer et al.). Characterization and Substrate Specificities of Various Mouse Kallikreins (O.U. Beg, M. Uddin). Natural Occurrence of Enzymes Linked to Inorganic Supports: Venice Lagoon and Internal City Canals (N. Sabil et al.). New Developments on Human Milk Protein Composition and Function: Human Milk as a Model for the Production of Dietetic Milks (A. Conti, G. Giuffrida). Structure-Function of Two Membrane Protein Systems Involved in Transfer of Electrical Charge (W.A. Cramer et al.). The Use of Metal Ions as Spectroscopic Probes in the Elucidation of Pka's of Small Molecules (B. Farzami). Structures and Functions of Leginsulin and Leginsulinbinding Proteins (H. Hirano). From Structure to Therapy? (L.N. Johnson). New Insights into the Molecular Structure of the Agonists Binding Site of Protein Kinase C by Pseudoreceptor Modeling (G. Krauter et al.). The Use of Synchrotron Radiation in Protein Crystallography (P.F. Lindley). 13 additional articles. Index.