Practical Biostatistics (2nd Ed.) A Step-by-Step Approach for Evidence-Based Medicine
Auteurs : Suchmacher Mendel, Geller Mauro
Practical Biostatistics: A Step-by-Step Approach for Evidence-Based Medicine, Second Edition presents a complete resource of biostatistical knowledge meant for health sciences students, researchers and health care professionals. The book's content covers the investigator?s hypothesis, collective health, observational studies, the biostatistics of intervention studies, clinical trials and additional concepts. Chapters are written in a didactic way, making them easier to comprehend by readers with little or no background on statistics. Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision-making using statistical analyses of scientific methods and outcomes to drive further experimentation and diagnosis.
With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or hands-on guide on how to effectively incorporate biostatistics in clinical trials and research projects.
Part 1: The Investigator's Hypothesis 1. Investigator's Hypothesis and Expression of its Corresponding Outcome
Part 2: Collective Health 2. Disease Frequency Measures 3. Health Indicators 4. Epidemiological Studies 5. Pharmacoeconomics
Part 3: Observational Studies 6. Basic Concepts in Observational Studies 7. Determination of Association Strength Between an Exposure Factor and an Event in Observational Studies 8. Increasing Accuracy in Observational Studies
Part 4: Biostatistics of Intervention Studies - The Clinical Trials 9. The Intervention Studies 10. N Estimation and N Assessment of a Published Trial 11. Organization of Variables and Endpoints 12. Measures for Results Expression of a Clinical Trial 13. Determination of Normality or Non-Normality of Data Distribution 14. Hypothesis Testing 15. Correlating Sample Data with the General Population - 95% Confidence Interval Summarizing the Steps
Part 5: Additional Concepts in Biostatistics 16. Individual and Collective Benefit and Risk Indexes Inferable from Intervention Studies 17. Statistical Assessment of Diagnostic Tests for the Clinic 18. Systematic Reviews and Meta-Analyses 19. Correlation and Regression 20. Per Protocol Analysis and Intention-to-Treat Analysis
Mauro Geller, MD, PhD, holds an MD degree from Teresopolis University Medical School, a PhD in Clinical Medicine from Federal University of Rio de Janeiro, and a Post-doc in Immunogenetics from Harvard University. He has extensive experience in the field of clinical immunology, especially in the areas of clinical medicine, tumoral immunology, genetics and immunodiagnostics. Dr. Geller is founding member and current medical director of the Brazilian National Neurofibromatosis Center; fellow of the American College of Physicians and of the Royal Society of Medicine; member of the European Society of Gene Therapy; and member of the Brazilian Societies of Immunology, Microbiology and Genetics. He is Board Certified in Internal Medicine, Immunology, Allergy and Public Health. Dr. Geller also has extensive experience with research in the areas of immunology, microbiology and genetics, as well as with clinical research, and has published 137 papers, 8 book chapters, and 4 books. He also serves as ad hoc advisor to the Brazilian National Institute of Health (ANVISA) and is member of the clinical staff of Hospital Israelita Albert Einstein.
- Explains biostatistics in a didactic way for students, researchers and professionals of health sciences with little or no background on mathematics
- Presents a new section dedicated to epidemiology and public health, broadening content from the previous edition
- Written by medical doctors with vast experience on biostatistics and teaching who develop the content based on real cases for better applicability by readers
Date de parution : 06-2021
Ouvrage de 206 p.
19x23.4 cm