Pharmacogenomics of Alcohol and Drugs of Abuse
Coordonnateurs : Dasgupta Amitava, Langman Loralie J.
Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy.
Applying
Pharmacogenomics Principles and Molecular Mechanism of Action of Alcohol and Abused Drugs. Alcohol: Use and Abuse. Slate and Trait Markers of Alcohol Abuse. Genetic Aspect of Alcohol Metabolism and Abuse. Introduction to Drug Abuse. Pharmacogenomics of Amphetamine and Related Drugs. Genetic Aspect of Cocaine Metabolism and Abuse. Genetic Aspect of Marijuana Metabolism and Abuse. Genetic Aspect of Opiate Metabolism and Addiction. Pharmacogenomics Aspect of Addiction Treatment. Methodologies in Pharmacogenomics Testing.
Amitava Dasgupta is a Professor of Pathology and Laboratory Medicine at the University of Texas-Houston Medical School. Loralie Langman is an Associate Professor of Laboratory Medicine at the Mayo Clinic, Rochester, Minnesota.
Date de parution : 09-2019
15.6x23.4 cm
Date de parution : 04-2012
Ouvrage de 256 p.
15.6x23.4 cm
Thèmes de Pharmacogenomics of Alcohol and Drugs of Abuse :
Mots-clés :
Opioid Receptor; CYP2D6 Genotype; opioid; FAAH; receptor; Cannabinoid Receptors; single; CB1 Receptor; nucleotide; CYP2B6 Polymorphism; polymorphism; GWAS; genome; Pharmacogenomic Studies; wide; ANKK1 Gene; association; ABCB1 Polymorphism; studies; Fetal Alcohol Spectrum Disorders; cannabinoid; Fetal Alcohol Syndrome; Brain Damage; CYP2D6 UMs; High Risk; CYP2B6 Genotype; CYP2D6 Pm; Ultrarapid Metabolizers; Moderate Alcohol Consumption; Target DNA; Poor Metabolizers; Cocaine Dependent Subjects; Ecgonine Methyl Ester; Cocaine Negative Urines; CSMD1