Part One: Foundations in Pathophysiology. Unit 1: Theoretical Perspective. Concepts and Theories of Pathophysiology. Unit 2: Cellular Perspective. Cell Structure and Intercellular Communication. Cellular Nutrition and Energy Metabolism. Cellular Electrophysiology: Action Potentials and Conduction. Cellular Mechanism of Muscle Contraction. Cellular Development: Genetic Regulation, Embryology, And Aging. Cellular Development: Congenital Defects and Neoplasia. Unit 3: The Cellular Environment. Fluid Balance. Electrolyte Balance. Acid-Base Balance. Thermoregulation. Part Two: Pathophysiology of Organ Systems. Unit 4: Hematologic Systems. Hematopoiesis and Related Disorders. Inflammation, Immunity, And Related Disorders. Disorders of Hemostasis and Fibrinolysis. Unit 5: Cardiovascular System. Disorders of Circulation. Cardiac Failure. Cardiac Dysrhythmia. Unit 6: Respiratory System. Disorders of Pulmonary Ventilation. Disorders of Gas Transport and Exchange. Unit 7: Renal-Urinary System. Disorders of Renal and Urinary Function. Unit 8: Neurologic System. Disorders of Cortical Function. Disorders of Motor and Autonomic Function. Disorders of Sensory Function. Unit 9: Gastrointestinal System. Disorders of Motility and Secretion. Disorders of Ingestion, Digestion, And Absorption. Disorders of the Liver and Biliary System. Unit 10: Endocrine System. Hypothalamic and Pituitary Disorders. Thyroid and Parathyroid Disorders. Disorders of the Adrenal Cortex and Endocrine Pancreas. Unit 11: Reproductive System. Disorders of the Male Reproductive System. Gynecological and Breast Disorders. Unit 12: Pregnancy and Neonatal Period. Disorders Related to Pregnancy and Lactation. Neonatal Disorders. Unit 13: Musculoskeletal System. Disorders of the Bones and Joints. Muscle Disorders and Effects of Exercise. Unit 14: Integumentary System. Dermatologic Disorders. Appendices.