Particulate Interactions in Dry Powder Formulation for Inhalation

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles and factors in pharmaceutical powder technology, critically reviews some of the studies carried out in dry powder formulation development, and proposes possible strategies for improving their efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).

1. Interparticulate Forces 2. Interparticulate Forces in Pharmaceutical Powders 3. Medicinal Aerosols 4. Particle Interactions with Air Streams 5. Particulate Interactions in Dry Powder Aerosols 6. Measurement of Cohesion, Adhesion and Dispersion of Powders 7. Physical Characterisation of Pharmaceutical Powders

Academic and Professional Practice & Development

Zeng, Xian Ming; Martin, Gary Peter; Marriott, Christopher