OMICS Biomedical Perspectives and Applications

A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research.

After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences.

While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.

SECTION I: Methodology and Application

Bioinformatics: A Brief Introduction to Changing Trends in Modern Biology

Nutrigenomics

Omics Approaches in Toxicology Research and Biomedical Applications

Stem Cells: Basics and Therapeutic Applications

Emerging Trends of Nanotechnology in Omics-Based Drug Discovery and Development

Magnetic Nanoparticles in Biomedical Applications

High-Throughput Screening in Medical Diagnosis and Prognosis

High-Throughput Omics: The Application of Automated High-Throughput Methods and Systems for Solutions in Systems Biology

Safety in Diagnostic Imaging Techniques Used in Omics

SECTION II: Empirical Research

Molecular Genetics of Human Cancers: Modulation of the Tumor Suppressor Function of RB1 Gene Product in Human Vestibular Schwannomas

Forward Genetics Approach in Genomics: Functional Identification of Unknown Genes

Proteomics of Phagosomal Pathogens: Lessons from Listeria monocytogens and New Tools in Immunology

SECTION III: Computational and Systems Biology

In a Quest to Uncover Governing Principles of Cellular Networks: A Systems Biology Perspective

Intermolecular Interaction in Biological Systems

Implanted Brain-Machine Interfaces in Rats: A Modern Application of Neuromics

SECTION IV: Therapeutics

Pharmacogenomics in Development of Disease-Specific Therapeutic Strategy

Omics Approaches in Cancer Biomarker and Targeted Anticancer Drug Discovery

Recent Advances in MicroRNA Expression Profiling Toward a Molecular Anatomy of Tumorigenesis and Applications for Diagnosis, Prognosis, and Therapeutics

Marine Metabolomics in Cancer Chemotherapy

Genome-Wide Association Studies of Type 2 Diabetes: Current Status, Open Challenges, and Future Perspectives

Cardiac Channelopathies: Applications of Genomics and Proteomics in Diagnosis and Therapy

Toward an Omic Perspective on Infectious Disease and Its Therapy: Integrating Immunoinformatics, Immunomics, and Vaccinomics

NeuroAIDS and Omics of HIV Vpr

Neurogenetics and Nutrigenomics of Reward Deficiency Syndrome

SECTION V: Future Perspective

Future Perspective: Paving a Path to Optimization of Health