Neurosecretion, Softcover reprint of the original 1st ed. 1988 Cellular Aspects of the Production and Release of Neuropeptides

This volume collects together the Proceedings of the Tenth International Symposium on Neurosecretion which was held in Bristol in September 1987. This series of symposia began with a meeting in Naples in 1953 and it was particularly gratifying to welcome two members of that original gathering, Berta Scharrer and Ellen Thomsen, to the 10th Symposium. The acceptance of the invitation to meet in Bristol gave particular pleasure to the Local Organising Committee because it was the first time that a former venue was revisited - the 3rd Symposium was organised in Bristol by Hans Heller in 1961 and we were very glad that his widow, Josephine, was able to be the Guest-of-Honour at the banquet of our 10th symposium. Neurosecretion has diversified considerably since the first meeting in 1953. From the outset, the local committee decided to focus the meeting by organising it under the title "Cellular aspects of the production and release of neuropeptides. " Having sought advice from the International Committee for Symposia on Neurosecretion, we invited 28 scientists from throughout the world to present their work on aspects ranging from the organisation of the gene through to the electrical properties of peptide-secreting neurones. The progress of studies in neurosecretion owes much to the comparative approach and we attempted to reflect this in the programme of the tenth symposium by inviting the speakers, to illustrate the various aspects of neuropeptide secretion, from among scientists working with systems in many parts of the animal kingdom.

Molecular Biology and Biosynthesis of Neuropeptides.- Oxytocin and Vasopressin: After the Genes, What Next?.- The Evolution of FMRFamide-Like Neuropeptide Genes.- Developmental and Molecular Studies of Neurons That Express FMRFamide-Related Genes in Insects.- The Role of RNA Splicing and Post-Translational Proteolytic Processing in the Biosynthesis of Neuropeptides.- Precursors of Urotensins and Their Co-Expression in the , Caudal Neurosecretory System.- In Situ Hybridization Study of Neurohypophysial Hormone mRNAS.- The Release of Enkephalin-Containing Peptides from the Adrenal Gland in Conscious Calves.- Localization of Neuropeptides.- Modern Microscopical Imaging Techniques for the Study of the Neuroendocrine System.- Combined Use of Lectin Histochemistry and Immunocytochemistry for the Study of Neurosecretoon.- Mapping and Analysis of Receptors for Neurohypophyseal Peptides Present in the Brain.- Somatostatin and Neuropeptide Y: Coexistence in the Hippocampus and Alterations in Alzheimer’s Disease.- Bioactive Peptides at the Neuromuscular Junction of Insects.- The Role of Head Activator in Cell Growth and Control Processes.- Cell Biology of Neuropeptide Secretion.- Release of Neuropeptides from Magnocellular Neurones: Does Anatomical Compartmentation Have a Functional Significance?.- Biosynthesis and Release of Multiple Peptides by the Caudodorsal Cells of Lymnaea Stagnalis.- Emerging Identity in Cytophysiology of Synaptic and Neurosecretory Terminals.- Isolated Neurohypophysial Nerve Endings, a Promising Tool to Study the Mechanism of Stimulus-Secretion Coupling.- Neuronal-Glial and Synaptic Plasticity in the Adult Oxytocinergic System.- Electrical Activity of Peptidergic Neurones Sponsored by Upjohn Ltd.- Contributions of Electrophysiology to the Study ofNeurosecretion.- Electrical Activity of Peptidergic Neurones and Its Relation to Hormone Release.- Rhythmic Patterns of Discharge from Preoptic Neurones: Relationship to LH Release in Conscious Rabbits.- Electrical Attributes of Neurosecretory Terminals and Their Relationship to Secretion.- Neuroanatomical and Electrophysiological Analysis of the Brain-Sinus Gland Neurosecretory System in a Crustacean.- Intrinsic and Synaptic Factors Regulating Mammalian Magnocellular Neurosecretory Neuron Activity.- Intrinsic Electrophysiological Regulation of Firing Patterns of Bursting Neurons in Aplysia.- The Neonatal Rat Supraoptic Neurone in Culture: Development of a Model for Control of Peptidergic Secretion.- Effects of Atrial Natriuretic Polypeptide and Angiotensin II on the Supraoptic Neurons in Vitro.- Poster Presentations.- Participants.