Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

Langue : Anglais

Coordonnateurs : Faingold Carl, Blumenfeld Hal

Couverture de l’ouvrage Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

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Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy.

With chapters authored by experts in each topic, this book advances the understanding of:

How the brain carries out important tasks via networks
How these networks interact in normal brain function
Major mechanisms that control network function
The interaction of the normal networks to produce more complex behaviors
How brain disorders can result from abnormal interactions
How therapy of disorders can be advanced through this network approach

This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders.

1. Introduction to Neuronal Networks of the Brain
2. Network Computer Modeling
3. Functional Magnetic Resonance Imaging in Epilepsy: Methods and Applications Using Awake Animals
4. Network Experimental Approaches: Inactivation, Microinjection, Neuronal Stimulation, and Recording
5. Network Experimental Approaches – ex vivo and ex vivo Networks
6. Network Imaging and Neuronal Firing
7. Network Control Mechanisms - Neuroactive Substances and Cellular Inputs
8. Network Control Mechanisms – Volume Transmission
9. Bursting in the Brain - From Cells to Networks
10. Network Control Mechanisms – Cellular Milieu
11. Neuronal Network Mechanisms - Sex and Development
12. Astrocytic Regulation of Synapses, Neuronal Networks and Behavior
13. The Fear Memory Network
14. Orchestration of the Circadian Clock Network by the Suprachiasmatic Nucleus
15. mTOR Signaling in Cortical Network Development
16. Network Control Mechanisms - Synaptogenesis and Epilepsy Development
17. The Brain and Spinal Cord Networks Controlling Locomotion
18. The Brainstem Respiratory Network
19. Visual Network
20. Auditory Neuronal Networks and Chronic Tinnitus
21. Consciousness and Subcortical Arousal Systems
22. Networks of Normal and Disordered Sleep
23. Networks for the Modulation of Acute and Chronic Pain
24. Networks in Mood and Anxiety Disorders
25. Neuronal Networks and Therapeutics in Neurodegenerative Disorders
26. Neuronal Networks in Epilepsy: Comparative Audiogenic Seizure Networks
27. Physiological and Pathophysiological Expansion of Neuronal Networks
28. Neuronal Network Plasticity and Network Interactions are Critically Dependent on Conditional Multireceptive (CMR) Brain Regions
29. Neuronal Network Interactions in the Startle Reflex, Learning Mechanisms, and CNS Disorders, Including Sudden Unexpected Death in Epilepsy
30. Emergent Properties of Neuronal Networks
31. Neuronal Network Involvement in Stimulation Therapies for CNS Disorders
32. Neuronal Network Effects of Drug Therapies for CNS Disorders
33. Future Trends in Neuronal Networks - Selective and Combined Targeting of Network Hubs

Neuroscience researchers, clinical neuroscience practitioners, neuropharmacologists

Carl L. Faingold is an American neuroscientist who is a Distinguished Professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois; he is a founding faculty member of both the department and the School of Medicine.
Hal Blumenfeld is a Professor of Neurology, Neuroscience, and Neurosurgery at Yale University. He is an expert on brain mechanisms of consciousness and on altered consciousness in epilepsy. As director of the Yale Clinical Neuroscience Imaging Center (CNIC) he leads multi-disciplinary research and is also well known for his teaching contributions in neuroanatomy and clinical neuroscience.

Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant
Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders
Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain
Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available