Natural Killer T cells, 2012 Balancing the Regulation of Tumor Immunity Cancer Drug Discovery and Development Series

Preface.-  Introduction: Mechanisms of NKT cell-mediated adjuvant activity and function of iPS-derived NKT cells.- Structure and Recognition of Antigens for Invariant NKT Cells.- Invariant NKT cell-based vaccine strategies.- Immune regulation of tumor immunity by NKT cells.- The Regulation of CD1d⁺ and CD1d^- tumors by NKT Cells.- DC-based immunotherapy targeting NKT cells.- Therapeutic Approaches Utilising NKT Cells.- NKT Cells of Cancer Patients & How Models can Inform Therapeutic Plans.- Understanding the role of Natural Killer T (NKT) cells in hematologic malignancies: progress and challenges.- Clinical trials with α-galactosylceramide (KRN7000) in advanced cancer.- Clinical trials of invariant Natural Killer T cell-based immunotherapy for cancer.- Index.