Metabolic Phenotyping in Personalized and Public Healthcare
Coordonnateurs : Nicholson Jeremy, Darzi Ara, Holmes Elaine, Lindon John C.
2. The Development of Metabolic Phenotyping - A Historical Perspective
The development of metabolic phenotyping - a historical perspective
3. Phenotyping the Patient Journey
4. Surgical Spectroscopy
5. High Throughput Metabolic Screening
6. Pharmacometabonomics and Predictive Metabonomics: New Tools for Personalised Medicine
7. Population Pehnotyping, Exposomics and MWAs
8. Handing on health to the next generation: Early Life Exposures
9. The Ageing Superorganism
10. Phenome Centers and Global Harmonization
11. From Databases to Big Data
12. Modeling People and Populations: Exploring Medical Visualization Through Immersive Interactive Virtual Environments
13. Future Visions for Clinical Metabolic Phenotyping: Prospects and Challenges
Head of Biosurgery and Surgical Technology, Hamlyn Chair of Surgery, Imperial College London, London, UK
Head of Computational and Systems Medicine, Professor of Chemical Biology, Imperial College London, London, UK
Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK
- Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making
- Discusses longitudinal sampling from individual patients for stratified medicine
- Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions
- Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease
- Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England
Date de parution : 02-2016
Ouvrage de 428 p.
15x22.8 cm
Thème de Metabolic Phenotyping in Personalized and Public Healthcare :
Mots-clés :
Ageing; Antibiotics; Autism; Big data; Bio-effect monitoring; Biofluid; Biofluid analysis; Biofluids; Bioinformatics; Biomarkers; Biomedical imaging; Biomedicine; Biomonitoring; Cancer; Chromatography; Chronic disease; Cost-benefit; Data exchange; Data management; Data warehousing; Databases; Diabetes; Diagnosis; Disease; Disease biomarkers; Epidemiology; Exposome; Exposure biomarkers; Gene-environment interaction; Genomics; Gestational diabetes; Health care; High-resolution metabolomics; High-throughput analytics; Immersive; Infection; Interaction; Interoperability; Malnourishment; Mass spectrometry; Metabolic phenotype; Metabolic phenotyping; Metabolic screening; Metabolomics; Metabonomics; Metagenome; Microbiome; Milk; NMR; NMR spectroscopy; Nuclear magnetic resonance; Nuclear magnetic resonance mass spectrometry; Obesity; Omics; Patient journey; Personalized Medicine; Personalized health care; Personalized medicine; Pharmaceuticals; Pharmaco-metabolomics; Pharmaco-metabonomics; Phenome center; Phenome centers; Phenomes; Phenomics; Population screening; Pre-eclampsia; Precision medicine; Premature birth; Prognosis; Proteomics; Public health; REIMS-DESI i-Knife personalized health precision surgery; Stratified medicine; Surgery metabonomics; System medicine; Systems biology; Therapy; Toxicity; Virtual environment; Visualization; -omics; Translational biology; surgical metabonomics; population profiling; systems metabonomics; metabolome-wide association studies