Cellular Responses in Sepsis.- The Role of Toll-like Receptors in Sepsis.- The Emerging Role of RAGE in Sepsis.- Oxidative Stress in Sepsis: Implications on Liver Protein Patterns and Analysis via Modified Proteomics Technology.- HSP90: The Unsung Villain of Sepsis?.- The Role of Extracellular Heat Shock Proteins in Cellular Inflammation and Injury.- Quantitative in vivo Protein Synthesis as a Measure of Immune Function.- Fluid Resuscitation and Immunomodulation in the Critically III.- Cellular Dysfunction.- Mitochondrial Dysfunction and Critical Illness Myopathy.- Lactic Acidosis and Hyperlactatemia.- Cardiovascular Dysfunction.- Physiology and Pathophysiology of the Natriuretic Peptide System.- Heart Failure as a Co-Morbidity in the ICU.- The Vascular Bed during Critical Illness: Evaluation in Animal Models.- Hemodynamic Monitoring.- Intensive Care Echocardiography.- Intrathoracic Blood Volume: Clinical Applications.- Hemodynamic Management Guided by Esophageal Doppler.- Less Invasive Cardiac Output Monitoring: Characteristics and Limitations.- Pulse Pressure Analysis.- Pulse Pressure Variations in Managing Fluid Requirement: Beware the Pitfalls!.- Minimally Invasive Hemodynamic Monitoring Using the Pressure Recording Analytical Method.- Coagulopathies.- Thrombotic Microangiopathy Syndrome in the ICU.- Altered Functionality of von Willebrand Factor in Sepsis and Thrombocytopenia — Potential Role of the vWF Cleaving Protease ADAMTS-13.- Coagulopathy in the Critically Injured Patient.- Critical Bleeding in Blunt Trauma Patients.- Trauma: Bleeding, Coagulopathy, and Blood Component Transfusion.- Hemostatic Resuscitation.- Effects of Plasma Substitutes on Coagulation.- Blood Transfusions.- Transfusion as a Risk Factor for ALI and ARDS.- Red Blood Cell Desialylation in Critically III Patients: An Underestimated Cause of Anemia.- Cardiopulmonary Resuscitation.- Clinical Predictors of Physiological Deterioration and Subsequent Cardiorespiratory Arrest among Hospitalized Patients.- Cardiocerebral Resuscitation: A Better Approach to Out-of-Hospital Cardiac Arrest.- Induced Hypothermia for Neuroprotection: Understanding the Underlying Mechanisms.- Acute Lung Injury.- Hyaluronan in Acute Lung Injury.- Aspiration-induced Lung Injury: Experimental and Human Studies.- Pulmonary Edema in Organ Donors and Lung Transplant Recipients: Is there a Role for Beta-adrenergic Agonists?.- Respiratory Support.- Current Concepts of Airway Management in the ICU and the Emergency Department.- Use of Continuous Positive Airway Pressure in Critically III Patients.- Non-invasive Respiratory Support in Pre-term Neonates and Pediatric Patients with Respiratory Failure.- Fast and Slow Compliance: Time, in Addition to Pressure and Volume, is a Key Factor for Lung Mechanics.- Does Ventilator-induced Lung Injury Initiate Non-pulmonary Organ Dysfunction?.- Monitoring in Respiratory Failure.- Electrical Impedance Tomography and its Perspectives in Intensive Care Medicine.- Electrical Impedance Tomography for Monitoring of Regional Ventilation in Critically III Patients.- Volumetric Capnography for Monitoring Lung Function during Mechanical Ventilation.- Monitoring Respiratory Drive and Respiratory Muscle Unloading during Mechanical Ventilation.- Weaning from Mechanical Ventilation.- Weaning from Mechanical Ventilation.- Liberation from Mechanical Ventilation in Acutely Brain-injured Patients.- Non-invasive Ventilation for Respiratory Failure after Extubation.- Burn Injury.- Importance of Airway Management in Burn and Smoke Inhalation-induced Acute Lung Injury.- Metabolic Changes Following Major Burn Injury: How to Improve Outcome.- Antibiotic Dosing in Burn Injury: Should We be Looking at the Tissues more Closely?.- Metabolic Support.- Defining Relative Adrenal Insufficiency in the Critically III: The ACTH Test Revisited.- Enteral Nutrition in the Critically III: Should We Feed into the Small Bowel?.- Tight Energy Balance Control for Preventing Complications in the ICU.- Bacteriological Problems.- Acute Pneumonia and Importance of Atypical Bacteria.- Antibiodic Resistance in the Intensive Care Unit.- Fungal Infections.- Systemic Candida Infection in the ICU.- Candida Colonization Index in the Management of Critically III Patients.- Antifungal Therapy in Surgical ICU Patients.- Hepatosplanchnic Failure.- Splanchnic Perfusion and Oxygenation in Critical Illness.- Liver Failure: Diagnostic Assessment and Therapeutic Options.- Immunoparalysis in Liver Disease.- Hepatorenal Syndrome.- Renal Failure.- Sepsis and Acute Renal Failure.- Sixty Years of ‘Extended Dialysis’ in the ICU.- Anticoagulation in CRRT: Systemic or Regional?.- Plasma Filtration Adsorption Dialysis: A New Experimental Approach to Treatment of Sepsis and MOF.- Sleep and Delirium.- Sleep in the ICU.- Sleep and Delirium in the Critically III: Cause or Effect?.- Delirium, Recall and the Post-ICU Challenge.- Contemporary Issues.- Morbid Obesity as a Determinant of Outcome in the Critically III.- Patient Safety Management System in Pediatric ICUs.- Information Exchange in Intensive Care: How can we Improve?.- Catastrophic Anachronisms: The Past, Present and Future of Disaster Medicine.- Health Services Research and Critical Care.- Healthcare Disparities in Critically III Patients.- International Comparisons of Intensive Care: Understanding the Differences.