Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development, Softcover reprint of the original 1st ed. 1993
Langue : Anglais
Coordonnateurs : Yacobi A., Skelly J.P., Shah Vinod P., Benet L.Z.
Proceedings of a conference sponsored by the American Association of Pharmaceutical Scientists, the U.S. Food and Drug Administration, and the American Society for Clinical Pharmacology and Therapeutics, held in Arlington, Virginia, April 24-26, 1991
Introduction: The Case for Preclinical Pharmacodynamics (G. Levy). Preclinical Pharmacokinetic and Pharmacodynamic Studies: Pharmacokinetics and Drug Metabolism in Animal Studies (G.G. Fitzgerald). Methodology for Preclinical Pharmacodynamic Studies: Preclinical Pharmacodynamics of Central Nervous System Active Agents (M. Danhof et al.). Preclinical and Clinical Pharmacokinetics: The Role of Pharmacokinetics in the Drug Development Process (L.Z. Benet). Clinical Pharmacodynamics: The Value of PlasmaWayfarin Measurement (R.A. O'Reilly). Application of Pharmacodynamics and Pharmacokinetics in the Drug Development Process: ConcentrationControlled Trials (L. Sanathanan, C.C. Peck). Summary Report: Opportunities for Integration of Pharmacokinetics, Pharmcodynamics, and Toxicokinetics in Rational Drug Development. 19 additional articles. Index.
Date de parution : 05-2013
Ouvrage de 270 p.
17x24.4 cm
Thème d’Integration of Pharmacokinetics, Pharmacodynamics, and... :
Mots-clés :
drug; drug development; kinetics; metabolism; pharmaceutical; pharmacodynamics; pharmacokinetics; pharmacology; research
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