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Heterocycles in natural product synthesis (hardback)

Langue : Anglais

Coordonnateurs : Majumdar Krishna C., Chattopadhyay Shital K.

Couverture de l’ouvrage Heterocycles in natural product synthesis (hardback)
There is an unbelievably large number of various heterocycles found in natural products. The synthesis of these compounds has always been a fascinating topic in organic chemistry, mainly because many of them are used in pharmaceutical and agrochemical active substances.

Filling a gap on the market, this handbook and ready reference is the first to discuss the usefulness of various heterocyclic systems in the synthesis of natural products. It is clearly structured for easy access to the information, with each chapter devoted to a certain class of heterocycle. For every natural product covered, a tabular presentation contains the particular heterocyclic ring system along with its biological profile, occurrence and most important physical properties, all supported by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products is covered in detail.

With its unique perspective and wealth of information, this is indispensable to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.


List of Contributors.

Part One Strained Heterocycles in the Synthesis of Natural Products.

1 Aziridines in Natural Product Synthesis (Candice Botuha, Fabrice Chemla, Franck Ferreira and Alejandro Pérez-Luna).

1.1 Introduction.

1.2 Synthesis of Natural Products Containing Aziridine Units.

1.3 Synthesis of Natural Products Involving the Transformation of an Aziridine Moiety.

1.4 Conclusion.


2 Azetidine and Its Derivatives (Hidemi Yoda, Masaki Takahashi and Tetsuya Sengoku).

2.1 Introduction.

2.2 Structural Description of Azetidines.

2.3 Synthetic Methodologies for the Formation of Azetidine Rings.

2.4 Synthesis of Mugineic Acids.

2.5 Synthesis of Penaresidins.

2.6 Structural Description of Azetidin-2-ones.

2.7 Synthetic Methodologies for the Formation of Azetidin-2-ones.

2.8 Synthesis of Penicillin.

2.9 Synthesis of Cephalosporin.

2.10 Conclusion.



3 Epoxides and Oxetanes (Biswanath Das and Kongara Damodar).

3.1 Introduction.

3.2 Epoxides in Natural Product Synthesis.

3.3 Oxetane in Natural Product Synthesis.

3.4 Conclusion.



Part Two Common Ring Heterocycles in Natural Product Synthesis.

4 Furan and Its Derivatives (Alicia Boto and Laura Alvarez).

4.1 Introduction.

4.2 Natural Products Containing the Furan Ring.

4.3 Furan Derivatives as Reagents in the Synthesis of Natural Products.

4.4 Summary.


5 Pyran and Its Derivatives (Hideto Miyabe, Okiko Miyata and Takeaki Naito).

5.1 Introduction.

5.2 Application of Pyran Moieties in the Synthesis of Natural Products.

5.3 Conclusion.


6 Pyrrole and Its Derivatives (Dipakranjan Mal, Brateen Shome and Bidyut Kumar Dinda).

6.1 Introduction.

6.2 Synthesis of Pyrrole Natural Products.

6.3 Synthesis of Non-pyrrole Natural Products from Pyrrole Derivatives.

6.4 Conclusion.



7 Indoles and Indolizidines (Sarah M. Bronner, G.-Yoon J. Im and Neil K. Garg).

7.1 Introduction.

7.2 Applications of Indoles and Indolizidines in the Synthesis of Natural Products.

7.3 Conclusion.



8 Pyridine and Its Derivatives (Paula Kiuru and Jari Yli-Kauhaluoma).

8.1 Introduction.

8.2 Application of the Pyridine Moiety in the Synthesis of Natural Products.

8.3 Conclusion.



9 Quinolines and Isoquinolines (Antonio Garrido Montalban).

9.1 Introduction.

9.2 Application of Quinolines and Isoquinolines in the Synthesis of Natural Products.

9.3 Conclusion.


10 Carbazoles and Acridines (Konstanze K. Gruner and Hans-Joachim Knölker).

10.1 Introduction to Carbazoles.

10.2 Total Synthesis of Carbazole Alkaloids.

10.3 Introduction to Acridines.

10.4 Synthesis of Acridines and Acridones.


11 Thiophene and Other...

Date de parution :

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18.2x25 cm

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