Genomics and health in the developing world (Monographs on medical genetics) Oxford Monographs on Medical Genetics Series

Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation, with particular emphasis on medical and health issues, in the emerging economies and countries of the developing world. With sections dedicated to fundamtals of genetics and genomics, epidemiology of human disease, biomarkers, comparative genomics, developments in translational genomic medicine, current and future health strategies related to genetic disease, and pertinent legislative and social factors, this volume highlights the importance of utilizing genetics/genomics knowledge to promote and achieve optimal health in the developing world. Grouped by geographic region, the chapters in this volume address: Inherited disorders in the developing world, including a thorough look at genetic disorders in minority groups of every continent.The progress of diagnostic laboratory genetic testing, prenatal screening, and genetic counseling worldwide. Rising ethical and legal concerns of medical genetics in the developing world. Social, cultural, and religious issues related to genetic diseases across continents. Both timely and vastly informative, this book is a unique and comprehensive resource for genetists, clinicians, and public health professionals interested in the social, ethical, economic, and legal matters associated with medical genetics in the developing world.

Part I: Genomics in Medicine and Health-General. Genes and Genomes in Health and Disease: The Human Variome Project and the Developing World. Human Genomic Variation Initiatives in Emerging Economies and Developing Countries. The Genomic Map of Population Diversity in Asia. Ancestry, Disease and Variable Drug Response in the Genomic Era. The Next Steps for Genomic Medicine: Challenges and Opportunities for the Developing World. Consumer Perspectives on Genomics and Healthcare. Transcultural Perspectives on Genetics and Genomics. Medical Genetics and Genomics Research in the Muslim World. The Progress of Genomics in the Developing World: Rising Social, Economic and Ethical Concerns. Genetic Outcomes of Consanguineous Marriages. Autosomal Recessive Conditions and Autozygosity Mapping. Genetic Contribution to Malaria Susceptibility and Resistance. Glucose 6-Phosphate Dehydrogenase Deficiency: Genetics, Pharmacogenetics and Malaria Selection. Infections, Genomics, and Global Public Health. Microbial Genomics and Global Health. Pharmacogenetics and Pharmacogenomics in the Developing World. Nutrigenomic Research in World Populations. Transgenic Foods and Nutritional Health in Developing Countries. The Burden of Inherited Disease in the Developing World: The Example of Inherited Blood Diseases. Health Implications of Inherited Disorders of Iron Overload. Inherited Factors in Diabetes Mellitus and Related Metabolic Disorders in the Developing World. Global Health Implications of Genetic Studies of Obesity and Type 2 Diabetes. Health Implications of Familial Hyperlipidemia. Global Health Implications of Inherited Renal Diseases. The Burden of Congenital Anomalies on Global Health. Inherited Eye Diseases in Developing Countries. Principles and Practice of Newborn Screening-The Lessons from the Developed World. Diagnostic Laboratory Genetic Testing. Models for the Developing World. Ethical Issues Arising in Medical Genetics in Developing Countries. Genetic and Genomics Services in Emerging Economies of the Developing World. Part II: Genomics in Medicine and Health-Regional. Africa. Anthropology and Population Heterogeneity in North Africa. The Genetic Landscape of Sub-Saharan African Populations. Genetic Disorders in North African Populations. Genetic Neurological Diseases in Tunisia. Hemoglobinopathies in Africa. The Burden of Birth Defects and Genetic Disease in Sub-Saharan Africa. Genetic Epidemiology of South Atlantic Oceanic Islands. Genetic Disorders in Minority Groups in South Africa. Hereditary Deafness in Southern Africa. Heritable Disorders of the Skeleton in South Africa. Heritable Disorders of Connective Tissue in South Africa. Genetic Perspectives of Tuberculosis in Southern Africa. Familial Cancer Syndromes in Africa. Genetic Counseling in South Africa. Prenatal Diagnostic Services and Prevention of Birth Defects in South Africa. Sociocultural Perspectives of Inherited Diseases in Southern Africa. Ethical, Legal, and SocioCultural Issues and Genetic Services in Southern Africa. The Genomic Research and Health Applications in South Africa. Hereditary Disorders in Arabs. Community Health Implications of Consanguinity in Arab Populations. Clinical Dysmorphology in the Arab World. The Population Genetics and Hereditary Diseases of Bahrain. Genetic Diseases in the Sultanate of Oman. Genetic Disorders in Lebanon: Challenges and Opportunities. Genetic Disease in Palestine and Palestinians. Genetic Skin Diseases in the Arab World. Hereditary Diseases of the Nervous System in Arabs. Preimplantation Genetic Diagnosis in Saudi Arabia. Asia-Pacific. Genomics for Universal Healthcare in Thailand. Screening Newborns in the Asia-Pacific Region. Clinical Dysmorphology and Birth Defects Registry in the Asia-Pacific Region. Prevention and Control of Thalassemia in Thailand. Inherited Metabolic Disorders in Thailand and the Asia-Pacific. Genetic Skeletal Dysplasias in Thailand. Medical Genetic Services in the Philippines. Chinese Subcontinent. Community and Public Health Genetics in China. Genetic Epidemiology in China. Traditional Chin

Dhavendra Kumar, MD, FRCP, FACMG, is Professor, the University of Glamorgan, and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom.