G Protein Coupled Receptors Structure
Auteur : CONN P. Michael
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain.
- G Protein Coupled Receptors: Techniques for Probing Structure
- Comformational Ensemble View of G Protein-Coupled Receptors and The Effect of Mutations and Ligand Binding
- Structural Evolution of G-Protein-Coupled Receptors: A Sequence Space Approach
- Directed Evolution of G Protein-Coupled Receptors for High Functional Expression and Detergent Stability
- The Role of Hydrophobic Amino Acids in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors
- Structure of ß-Adrenergic Receptors
- Advances in Methods to Characterize Ligand-Induced Ionic Lock and Rotamer Toggle Molecular Switch in G-Protein Coupled Receptors
- Crystallogenesis of Adenosine A2A Receptor – T4 Lysozyme Fusion Protein: A Practical Route for the Structure
- Probing GPCR Structure: Adenosine and P2Y Nucleotide Receptors
- Strategies for Studying the Ligand Binding Site of GPCRs: Photoaffinity Labeling of the VPAC1 Receptor, a Prototype of Class B GPCRs
- Expression of Mammalian G Protein-Coupled Receptors in Caenorhabditis Elegans
- Expression, Purification and Structural Analysis of Intracellular C-Termini from Metabotropic Glutamate Receptors
- Unnatural Amino Acid Mutagenesis of GPCRs Using Amber Codon Suppression and Bioorthogonal Labeling
- Mapping a Ligand Binding Site Using Genetically-Encoded Photoactivatable Crosslinkers
- Alternative mRNA Splicing of G Protein-Coulped Receptors
- Functional Residues of the CB1 Cannabinoid Receptor
- Continues the legacy of this premier serial with quality chapters authored by leaders in the field
- Covers G protein coupled receptors
- Contains chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain
Date de parution : 03-2013
Ouvrage de 440 p.
15x22.8 cm
Mots-clés :
G protein-coupled receptor; GPCR; Membrane protein; Protein production; Pichia pastoris; Expression system; Optimization; High throughput; Structure determination; X-ray; GPCRs; Seven-transmembrane receptors; Protein structure prediction; Mutagenesis; Functional selectivity; Conformational energy landscape; GPCR; Evolution; Sequence space; Multidimensional scaling; Adrenergic receptor; G protein-coupled receptor; Membrane protein stabilization; Insect cell expression; Affinity purification; X-ray c