Fundamentals of asymmetric catalysis

This book describes the essential aspects of enantioselective catalysis in a clear, logical fashion, with chapters organized by concept rather than by reaction type. Each concept in Fundamentals of Asymmetric Catalysis is supported by carefully selected examples of a wide range of catalysts, reactions and reaction mechanisms.

Introduction to Fundamentals of Asymmetric Catalysis. Modes of Asymmetric Induction. Lewis Acid and Lewis Base Catalysis. Beyond Lewis Acid and Lewis Base Catalysis. Asymmetric Induction in Enantioselective Catalysis. Nonclassical Two Point Catalyst Substrate Interactions. Chiral Poisoning, Chiral Activation, and Screening Achiral Ligands. Kinetic Resolution. Parallel Kinetic Resolution. Dynamic Kinetic Resolution and Dynamic Kinetic Asymmetric Transformations. Desymmetrization Reactions . Nonlinear Effects, Autocatalysis, and Autoinduction. Bifunctional, Dual, and Multifunctional Catalyst Systems. Asymmetric Catalysis with Homochiral Substrates: Double Diastereoselection. Multistep Asymmetric Catalysis. Supported Catalysts. Applications of Asymmetric Catalysis in Synthesis. Appendix. Index.