Functional Neural Transplantation III Primary and Stem Cell Therapies for Brain Repair, Part I
Auteur : DUNNETT Stephen B.
- Preface
- Transplantation in the Future
- Ethical Challenges for Using Human Cells in Clinical Cell Therapy
- Banking Stem Cells for Research and Clinical Applications
- Survival, Differentiation and Connectivity of Ventral Mesencephalic Dopamine Neurons following Transplantation
- Electrophysiological Investigations of Synaptic Connectivity between Host and Graft Neurons
- Nigral Grafts in Animal Models of Parkinson’s Disease. Is Recovery beyond Motor Function Possible?
- L-DOPA- and Graft-Induced Dyskinesia following Transplantation
- Current Status of Clinical Trials of Neural Transplantation in Parkinson’s Disease
- In vivo Imaging of the Integration and Function of Nigral Grafts in Clinical Trials
- Neuropathology in Transplants in Parkinson’s Disease: Implications for Disease Pathogenesis and the Future of Cell Therapy
- Derivation of Dopaminergic Neurons from Pluripotent Stem Cells
- Characterization and Criteria of Embryonic Stem and Induced Pluripotent Stem Cells for a Dopamine Replacement Therapy
- Skilled Motor Control for the Preclinical Assessment of Functional Deficits and Recovery following Nigral and Striatal Cell Transplantation
- Role of Experience, Training and Plasticity in the Functional Efficacy of Striatal Transplants
- In vivo Imaging of Integration and Function of Striatal Grafts in Rodent and Non-Human Primate Animal Models
- Clinical Trials of Neural Transplantation in Huntington’s Disease
- Derivation of Striatal Neurons from Human Stem Cells Pedro Viegas, Camille Nicoleau and Anselme L. Perrier
Stephen Dunnett and Anders Björklund
Fred H. Gage
Göran Hermerén
Glyn Stacey
Lachlan Thompson and Anders Björklund
Jan Tønnesen and Merab Kokaia
Mariah J. Lelos, Eilís Dowd and Stephen B. Dunnett
Emma L. Lane and Christian Winkler
Jonathan R Evans, Sarah L Mason and Roger A Barker
Marios Politis and Paola Piccini
Patrik Brundin and Jeffrey H. Kordower
Lorenz Studer
Oliver Cooper, Malin Parmar and Ole Isacson
Alexander Klein and Ian Q. Whishaw
Máté D. Döbrössy and Guido Nikkhah
Philippe Hantraye and Romina Aron Badin
Anne E. Rosser and Anne-Catherine Bachoud-Lévi
- Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
- Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
- All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Date de parution : 12-2012
Ouvrage de 448 p.
19x23.3 cm