Endometrial cancer vol uropean practice in gynaecology & obstetrics vol 5 (epgo) : ebcog series

European Practice in Gynaecology and Obstetrics is a series of books published under the auspices of EBCOG. In each volume, the specialist will find a review of basic science, recent concepts in pathophysiology, clinical aspects, imaging, treatment and unresolved problems or controversies, and up-to-date references . Endometrial carcinoma is the most common genital malignancy in the Western world and is the second after cervical carcinoma in developing countries. It is considered a disease of women over 40 years of age, with 2/3 occurring in the post-menopausal age. Most endometrial carcinomas are diagnosed in early stages and are associated with favourable outcome. The prognosis of advanced diseases is poor. Compelling data suggest that there are at least two pathogenic entities of endometrial carcinoma, one that is oestrogen related, and the other that arises from atrophic endometrium. Management of endometrial carcinoma has changed during the last two decades, mainly as a result of the introduction of surgical staging by FIGO. Controversies in performing proper surgical staging, however, exist. There are a number of other controversial areas that are discussed in this book. Similarly, recent advances in diagnosing, managing and screening endometrial carcinoma have been highlighted. One of the major steps made is the inclusion of lymph node dissection in the surgical treatment of uterine cancer. This is not a consensus book, but rather a collection of the views of experts. Guidelines are provided for practising gynaecologists based on current evidence, along with the opinions of the contributors to this volume. We do hope this book will be of value to all involved in the care of women with carcinoma of the endometrium.

CARCINOMA OF THE ENDOMETRIUM CONTENTS Preface Péter Bõsze. Epidemiology of endometrial carcinoma Paul Pharoah (UK). Histopathology and quantitative pathology Michael Wells (UK). Advances in endometrial cancer screening Ph. Descamps France. Symptoms, signs and clinical prognostic factors Fernando Motta and Carlos F. de Oliveira Portugal. DNA content and S-phase fraction in adenocarcinoma of the endometrium: prognostic significance Bengt Lindahl, Claes Tropé Norway. Molecular biology of the carcinoma of the endometrium Fernando J. Regateiro, Manuel C. Lemos, Henriqueta A. Coimbra Potugal. Immunology of endometrial cancer Gerald Gitsch (Austria), Petra Kohlberger (Germany?). Guidelines for staging endometrial carcinoma Hans G. Bender Germany. Imaging of endometrial carcinoma: clinical implications Attila Artner and Klára Szalai Hungary. Endometrial hyperplasia, diagnosis of endometrial carcinoma, hysteroscopy and endometrial ablation. Raimund Winter Austria. The place of laparoscopy in the management of endometrial carcinoma Daniel Dargent France. Standard surgical management of resectable tumours Ubeda A, Santiago Dexeus, Aurell R. Spain. The role of lymphadenectomy in endometrial cancer M.A. van Eijkeren The Netherlands. The place of primary and adjuvant radiation therapy Richard Greiner Schwitzerland. Chemotherapy and hormonal treatment of endometrial adenocarcinoma Jan B. Vermorken Belgium. Clear cell carcinoma of the endometrium Vernaeve H, Moerman Ph, Ignace Vergote Belgium. Uterine papillary serous carcinoma Tiziano Maggino and Angiolo Gadducci Italy. Cases for radical surgery: curative and salvage intent László Pálfalvi and László Ungár Hungary. Major considerations and practical guidelines for management Péter B?sze Hungary. Follow-up of endometrial adenocarcinoma Stelios Fotiou Greece