Congestive Heart Failure, 1994 Pathophysiology, Diagnosis, and Comprehensive Approach to Management

This book is the first to approach the field of congestive heart failure as a true subspecialty of cardiology and cardiovascular surgery. The text discusses the entire field of congestive heart failure: the basic pathophysiologic mechanisms; the underlying diseases; the effects of heart failure on the remainder of circulation; the mechanisms and results of pharmacologic therapy; the multiple surgical and multidisciplinary approaches to end-stage heart disease; and the ultimate prognosis of congestive heart failure in all of the areas of heart failure management. Thus, this text uniquely puts into perspective all of the features of congestive heart failure and its management for the cardiologist, cardiovascular surgeon, and general internist.

I. Historical Perspectives.- 1. Evolution of Concepts of Myocardial Function in the Treatment of Congestive Heart Failure in Man.- II. Pathophysiology of Congestive Heart Failure.- 2. Overview of Pathophysiology of Congestive Heart Failure.- 3. The Molecular and Cellular Biology of Heart Failure.- 4. Abnormalities in Cardiac Contraction: Systolic Dysfunction.- 5. Abnormalities in Cardiac Relaxation and Other Forms of Diastolic Dysfunction.- 6. Cardiac Remodeling in Congestive Heart Failure.- 7. The Role of the Pericardium in the Pathophysiology of Heart Failure.- 8. The Sympathetic Nervous System in Congestive Heart Failure.- 9. Nonadrenergic Hormonal Alterations in Congestive Heart Failure.- 10. The Peripheral Circulation in Heart Failure.- 11. Renal Salt and Water Handling in Congestive Heart Failure.- III. Differential Diagnosis of Congestive Heart Failure.- 12. Heart Failure Secondary to Coronary Artery Disease.- 13. The Cardiomyopathies.- 14. Inflammatory Heart Disease.- 15. Congestive Heart Failure as a Consequence of Valvular Heart Disease.- 16. Heart Failure Secondary to Congenital Heart Disease.- 17. Right Heart Failure.- 18. Other Causes and Contributing Factors to Congestive Heart Failure.- 19. The Pathology of Congestive Heart Failure.- IV. Pharmacologic Therapy of Congestive Heart Failure.- 20. Clinical Pharmacokinetics in Congestive Heart Failure.- 21. Diuretics.- 22. Digitalis Glycosides.- 23. Angiotensin-Converting Enzyme Inhibitor Therapy for Congestive Heart Failure: Rationale, Results, and Current Recommendations.- 24. Vasodilators.- 25. Beta-Adrenergic Receptor Agonists and Antagonists in Heart Failure.- 26. Phosphodiesterase Inhibitors in Heart Failure: An Overview.- V. Therapeutic Approach in Acute Congestive Heart Failure.- 27. Hemodynamic Monitoring, Pharmacologic Therapy, and Arrhythmia Management in Acute Congestive Heart Failure.- 28. Intraaortic Balloon Pumping in Congestive Heart Failure.- 29. Ventricular Assistance and Replacement.- 30. Dialysis and Hemofiltration for Congestive Heart Failure.- 31. Surgical Therapy for Acute Congestive Heart Failure.- VI. Approach to Patients with Chronic Congestive Heart Failure.- 32. The Diagnostic Evaluation of Patients with Heart Failure.- 33. Prognosis in Congestive Heart Failure.- 34. The Medical Management of Chronic Congestive Heart Failure.- 35. Arrhythmia in Patients with a Cardiomyopathy and Congestive Heart Failure.- 36. Pathogenesis and Therapy of Thrombosis in Patients with Congestive Heart Failure.- 37. Surgical Approaches to Chronic Congestive Heart Failure.- 38. Cardiac Transplantation.- VII. Future Directions.- 39. The Diagnosis and Management of Congestive Heart Failure: What Does the Future Hold?.