Clinical Trials in Oncology (3rd Ed.) Chapman & Hall/CRC Interdisciplinary Statistics Series
Auteurs : Green Stephanie, Benedetti Jacqueline
The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data.
Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.
Date de parution : 10-2016
15.6x23.4 cm
Date de parution : 06-2012
Ouvrage de 262 p.
15.6x23.4 cm
Thèmes de Clinical Trials in Oncology :
Mots-clés :
Data Monitoring Committee; Interim Analyses; data; Progression Free Survival; monitoring; SWOG S7924; committee; Survival Distributions; progression-free; Null Hypothesis; survival; Southwest Oncology Group; Single Arm Trials; hypothesis; Multi-arm Trial; cancer; Logrank Test; phase; Institutional Review Board; logrank; Hazard Ratio; Sample Size Calculation; Cancer Clinical Trials; SWOG Study; Stratification Factors; Confidence Interval; Poor Risk Patients; DLT; Accelerated Titration Designs; Mtd Estimate; Portal Vein Infusion; Patient Experience DLTs; Phase Ii; True Response Probability