Cell Membranes, Softcover reprint of the original 1st ed. 1984 Methods and Reviews

We are extremely pleased that all of the chapters in this volume provide up-to-date information on a variety of topics of interest to scientists working on membrane biology. As in the past, we have attempted to expedite the transition from submission of the manuscripts to publication in order to make the reviews as timely as possible. Cell biology and molecular biology are increasingly be­ coming concerned with the study of structural elements in cells and their assem­ bly. The rules which govern membrane synthesis, assembly and interaction of membrane components with other cellular elements, notably the cytoskeleton, are at the center of research in these fields. We will continue in subsequent volumes of this series to focus on these areas. We would welcome suggestions of topics which would benefit from a review at the present time. We thank all of the contributors for providing these very excellent reviews and for doing so in a timely fashion. Elliot L. Elson William A. Frazier Luis Glaser St. Louis, Missouri vii CONTENTS Chapter 1 Chemotactic Transduction in the Cellular Slime Molds William A. Frazier, Beth L. Meyers-Hutchins, Gordon A. Jamieson, Jr. , and Nancy J. Galvin 1. Introduction-Chemotaxis in the Cellular Slime Molds . . . . . . . . . . . 2. Receptors for Chemoattractants of the Cellular Slime Molds . . . . . . . 4 2. 1. The Folate Receptor of Vegetative D. discoideum . . . . . . . . . . . 4 2. 2. The cAMP Receptor of Aggregating D. discoideum . . . . . . . . . 6 3. Putative Transduction Events in D. discoideum . . . . . . . . . . . . . . . . . 10 3. 1. cGMP and Guanylate Cyclase . . . . . . . . . . . . . . . . . . . . . . . . . . .

1 Chemotactic Transduction in the Cellular Slime Molds.- 2 Leukocyte Chemotaxis: Mobilization of the Motile Apparatus by N-Formyl Chemotactic Peptides.- 3 The Interactions of Cells with Extracellular Matrix Components.- 4 The Human Erythrocyte as a Model System for Understanding Membrane Cytoskeleton Interactions.- 5 Regulation of Assembly of the Spectrin-Based Membrane Skeleton in Chicken Embryo Erythroid Cells.- 6 Assembly and Establishment of Membrane—Cytoskeleton Domains during Differentiation: Spectrin as a Model System.- 7 Role of the ?-Adrenergic Receptor in the Regulation of Adenylate Cyclase.- 8 Acetylcholine Receptor: Some Methods Developed to Study a Membrane-Bound Regulatory Protein.