Biochemistry (4^th Ed.)

This textbook 'Biochemistry' has become one of the most preferred text books (in India and many other countries) for the students as well as teachers in medical, biological and other allied sciences. The book has undergone three editions, several reprints, and revised reprints in a span of 13 years.

There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject.

This book, 'Biochemistry' is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.).

This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.

SECTION ONE

Chemical Constituents of Life

1 Biomolecules and the cell

2 Carbohydrates

3 Lipids

4 Proteins and amino acids

5 Nucleic acids and nucleotides

6 Enzymes

7 Vitamins

SECTION TWO

Physiological Biochemistry

8 Digestion and absorption

9 Plasma proteins

10 Hemoglobin and porphyrins

11 Biological oxidation

SECTION THREE

Metabolisms

12 Introduction to metabolism

13 Metabolism of carbohydrates

14 Metabolism of lipids

15 Metabolism of amino acids

16 Integration of metabolism

17 Metabolism of nucleotides

18 Mineral metabolism

SECTION FOUR

Clinical Biochemistry and Nutrition

19 Hormones

20 Organ function tests

21 Water, electrolyte and acid-base balance

22 Tissue proteins and body fluids

23 Nutrition

SECTION FIVE

Molecular Biology and Biotechnology

24 DNA-replication, recombination and repair

25 Transcription and translation

26 Regulation of gene expression

27 Recombinant DNA and biotechnology

SECTION SIX

Current Topics

28 Human genome project

29 Gene therapy

30 Bioinformatics

31 Metabolism of xenobiotics (detoxification)

32 Prostaglandins and related compounds

33 Biological membranes and transport

34 Free radicals and antioxidants

35 Environmental biochemistry

36 Insulin, glucose homeostasis, and diabetes mellitus

37 Cancer

38 Acquired immunodeficiency syndrome (AIDS)

SECTION SEVEN

Basics to Learn Biochemistry

39 Introduction to bioorganic chemistry

40 Overview of biophysical chemistry

41 Tools of biochemistry

42 Immunology

43 Genetics

APPENDICES

Answers to Self-assessment Exercises

i Abbreviations used in this book

ii Origins of important biochemical words

iii Common confusables in biochemistry

iv Practical biochemistry-principles

v Clinical biochemistry laboratory

vi Case studies with biochemical correlations

INDEX