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Bioactive Functionalisation of Silicones with Polysaccharides, 1st ed. 2018 Biobased Polymers Series

Langue : Anglais

Auteurs :

Couverture de l’ouvrage Bioactive Functionalisation of Silicones with Polysaccharides
This book covers the functionalisation of silicone surfaces with polysaccharides to improve their antimicrobial and antifouling properties, thus reducing the implant-related infections. The authors describe how silicone surfaces were chosen because silicone exhibits excellent biocompatible properties and is already being used for medical implants such as catheters, breast implants, prosthetics etc. The potential of polysaccharides such as cellulose, chitosan, hyaluronic acid, and other natural substances such as natural surfactants as coatings for silicones are also discussed, their effects are evaluated. With the aging of the population, the number of medical implants is growing and with it the number of infections associated with the use of implants.

Introduction 

1. Silicone in medical applications

1.1 Structure and properties of silicone

1.2 Applications of silicones in medicine

1.3 Urethral catheters

2. Catheter associated urethral tract infections

2.1 The role of biofilm formation

3. Polysaccharides in medical applications

3.1 Polysaccharide coatings 

4. Functionalisation of silicones with polysaccharides

4.1 Activation of silicone surfaces

4.2 General approaches of silicone functionalisation with polysaccharides

4.3 Novel approaches of silicone functionalisation with polysaccharides

5. Conclusions

References

Dr. Matej Bračič is an expert in studying interactions of molecular and polymer dispersions in liquids with solid surfaces and biological evaluation of both surfaces. His research work is focused on the preparation and characterization of nano and micro-dispersion, the preparation and characterization of solid surfaces by electrospinning, spin-coating, dip-coating and dip-casting methods, interactions with biomolecules (proteins, enzymes, bacteria) and the transfer of knowledge into the field of sensors for the production of bioactive sensors. His bibliography covers 65 units, of which 21 are original scientific articles, 29 are contributions at national and international conferences and 14 are final reports on national and international projects. He has 91 pure citations in the last 10 years and an h index of 7. He received an award at the International Conference IN-TECH 2014: Award for Science and Technology Transfer (World Association of Innovative Technologies) on 12 September 2014 in Leiria, Portugal. He is currently working as a postdoctoral researcher at the Laboratory for Characterisation and Processing of Polymers, Institute of Engineering Materials and Design, University of Maribor.


Prof. Dr. Simona Strnad, Dr. Tech. Sci. is an expert in structure and properties of fibrous materials and advanced materials engineering. Her research work is focused on investigations of structure/properties relationships of polymer materials and surface functionalization and characterization. Her bibliography comprises: 351 bibliographic items including 63 scientific papers, 7 Invited lectures, 6 book chapters, 2 patents and more than 60 research and industrial project collaborations, among them FP6 NMP3-CT-2005-500375: EPNOE – Polysaccharides; Network of Excellence “Polysaccharides” [COBISS.SI-ID 13864470]; FP7 NMP-2007-2.1.1-1 – SURFUNCELL – Nanostructured polymer-matrix composites “Surface functionalization of cellulose matrices using coatings of func

First exhaustive review of polysaccharide use as antibacterial and antifouling coatings for silicone implants

A comprehensive study of interfacial phenomena between silicones and various polysaccharide

Describes the novel use of a polysaccharide-surfactant complex coating

Date de parution :

Ouvrage de 75 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 52,74 €

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