Basic and Applied Bone Biology (2nd Ed.)
Coordonnateurs : Burr David B., Allen Matthew R.
Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology.
Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).
1. Bone Morphology and Organization2. Bone Cells3. Local Regulation of Bone Cell Function4. Bone Modeling and Remodeling5. Skeletal Imaging6. Skeletal Hard Tissue Biomechanics7. Techniques in Histomorphometry8. Skeletal Genetics: From Gene Identification to Murine Models of Disease9. Mechanical Adaptation10. Fracture Healing11. Craniofacial Biology, Orthodontics, and Implants12. Skeletal Growth and Development13. Calcium and Phosphate: Hormonal Regulation and Metabolism14. Nutrition15. Hormonal Effects on Bone Cells16. Metabolic Bone Diseases17. Pharmaceutical Treatments of Osteoporosis
Graduate students, medical fellows/residents, researchers, and academic clinicians in the fields of bone biology, endocrinology, osteology, rheumatology, and dentistry
Matthew R. Allen is an Associate Professor of Anatomy and Cell Biology at Indiana University School of Medicine. His research career, and interest in bone biology, began at Alma College during a summer research fellowship and continued during his years as a PhD student at Texas A&M (in Kinesiology) and post-doctoral fellow at IU School of Medicine. His research focuses on understanding how interventions can be maximized to strengthen the skeleton and his teaching duties include Medical Histology (to first year medical students) and Basic Bone Biology (to graduate students). He serves on the Editorial Board for the Journal of Bone and Mineral Research, BONE, and BoneKEY, and as an Associate Editor for Clinical Reviews in Bone and Mineral Metabolism. He has authored more than 70 research articles and 18 book chapters and reviews.
- Presents an in-depth overview of skeletal biology, from molecular to organ level
- Offers refresher level content for clinicians or researchers outside their areas of expertise
- Includes updated and complete references
- Incorporates expanded study questions at the end of each chapter for further exploration
- Covers topics relevant to a modern course in skeletal biology
Date de parution : 02-2019
Ouvrage de 478 p.
21.4x27.6 cm
