Autoimmune Neurology Handbook of Clinical Neurology Series

Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system.

Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease.

This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders.

Section 1 Introduction 1. Introduction to the field of autoimmune neurology - Angela Vincent and Sean J. Pittock

Section 2 Basic neurobiology 2. Signaling molecules of the CNS as targets of autoimmunity - Eduardo E. Benarroch 3. Blood brain barrier - Birgit Obermeier and Richard Ransohoff 4. Basic principles of immunology - Karen E. Hedin 5. Cellular and molecular outcomes of the targeted immune attack - Rita Balice-Gordon and Ankit Jain 6. Immunopathology: Autoimmune glial diseases and differentiation from MS - Claudia Francesca Lucchinetti 7. Immunopathology: Autoimmune neuronal diseases - Jan Bauer and Christian G Bien 8. Animal models of neurological autoimmunity - Hans Lassmann and Monica Bradl

Section 3 Clinical: autoimmune neurological disorders 9. Detection methods for neural autoantibodies - Patrick Joseph Waters 10. Approach to diagnosis and treatment - Sean J. Pittock and Jacqueline Palace 11. Voltage-gated potassium channel complex autoimmunity and the clinical syndromes - Sarosh Irani and Angela Vincent 12. Glutamate and GABA R autoimmunity and encephalopathies - Maarten Jan Titulaer 13. Epilepsy - Jeffrey Britton 14. Dementia - Bradley F. Boeve 15. Autoimmunity in neuropsychiatric disorders - Ester Coutinho and Angela Vincent 16. Vision loss - Gordon Plant 17. Autoimmune movement disorders - Andrew McKeon and Angela Vincent 18. Dysautonomia - Andrew McKeon and Eduardo E. Benarroch 19. Myelopathies - Eoin P. Flanagan 20. Autoimmune-mediated peripheral neuropathies and autoimmune pain - Christopher Klein 21. Neuromuscular junction disorders - Jan Verschuuren 22. Muscle disease - Andrew L Mammen 23. Sleep disorders - Michael Silber 24. Autoimmune AQP4 channelopathies and NMOSD - Vanda A. Lennon and Shannon R. Hinson 25. Autoimmune Neurological Disorders in Children - Mark Gorman and Ming Lim 26. CNS Vasculitis in Adults and Children - Susanne Maria Benseler 27. Current and future immunotherapy strategies in autoimmune neurology - Kevin O'Connor

Neuroscience researchers, clinical neurologists, neuroimmunology

• Includes comprehensive coverage of autoimmune neurology
• Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders
• Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities