Aqueous polymeric coatings for pharmaceutical dosage forms (Drugs & the pharmaceutical sciences, Vol. 176) (3^rd Ed.)

Thoroughly updated and expanded, this new 3rd edition provides the latest information on dosage, forms, film defects, and polymer characterization. Written by renowned leaders in the field, Aqueous Polymeric Coatings for Pharmaceutical Dosage Formsis easily the most comprehensive book available on the market today. New to the 3rd Edition: the interaction of drugs with functional polymers, the influence of processing parameters on coating quality, the stabilization of polymeric film coats, plastisizers and their applications in pharmaceutical coatings, adhesion of polymeric films to solid substrates, basic properties of latex and pseudolatex colloidal dispersions. Key topics included: polymer interactions with drugs and excipients, physical aging of polymeric films. A complete overview and in-depth analysis of recent advances in the field, which includes information on the latest equipment used to apply polymers to a pharmaceutical system, illustrated examples explaining the appropriate steps to be taken in order to solve formulation, processing and stability problems to achieve an optimized dosage form.

Latex Emulsions for Controlled Drug Delivery. Aqueous Polymeric Coating for Modified Release Oral Dosage Forms. Processing and Equipment Considerations for Aqueous Coatings. Mechanical Properties of Polymeric Films Prepared from Aqueous Polymeric Dispersions. Plasticizers and Their Application in Pharmaceutical Coatings. Defects in Aqueous Film-Coated Tablets. Adhesion of Polymeric Films. Influence of Pigments in the Properties of Polymeric Coating Systems. Process and Formulation Factors Affecting the Drug Release from Pellets Coated with the Ethylcellulose Pseudolatex Aquacoat. Chemistry and Application Properties of Polymethacrylate Coating Systems. Application of HPMC and HPMCAS to aqueous film coating of Pharmaceutical Dosage Forms. Physical Properties of HPMC Solutions and Their Role in the Film Coating Process and the Quality of the Coated Product. Use of Opadry, Sureteric, and Sureleease for Aqueous Film Coating of Pharmaceutical Solid Dosage Forms. Aqueous-based Coatings and Microparticles in Matrix Tablet Formulations. Polymer Interactions with Drugs and Excipients. Properties of Aqueous Pseudolatex Dispersions of Biodegradable Polymers. Physical Aging of Polymeric Film Coats