Alkaloids A Treasury of Poisons and Medicines

Langue : Anglais

Auteurs : Funayama Shinji, Cordell Geoffrey A.

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Alkaloids are a large group of structurally complex natural products displaying a wide range of biological activities. The purpose of Alkaloids: A Treasury of Poisons and Medicines is to classify, for the first time, the alkaloids isolated from the natural sources until now. The book classifies all of the alkaloids by their biosynthetic origins. Of interest to the organic chemistry and medicinal chemistry communities involved in drug discovery and development, this book describes many alkaloids isolated from the medicinal plants, including those used in Japanese Kampo medicine.

1: Alkaloids Derived from Phenylalanine and Tyrosine2: Alkaloids Derived from Tryptophan3: Alkaloids Derived from Ornithine (Arginine)4: Alkaloids Derived from Lysine 5: Alkaloids Derived from Proline6: Alkaloids Derived from Glutamic Acid7: Alkaloids Derived from Histidine8: Alkaloids Derived from 2,3-Diaminopropionic Acid9: Alkaloids Derived from Anthranilic Acid10: Alkaloids Derived from Nicotinic Acid11: Alkaloids Derived from Nucleic Acids and Related Compounds12: Alkaloids Possessing the Porphine Skeleton13: Alkaloids Derived from a m-C7N Unit14: Alkaloids Derived from Terpenoids15: Alkaloids Derived from Polyketides

Scientists in the natural products field, as well as chemistry, biochemistry and pharmacy students. Scientists working for pharmaceutical companies. Physicians, pharmacists and other professionals who are interested in Japanese Kampo medine.

Professor Shinji Funayama obtained his Ph.D. in natural product chemistry at Tohoku University (Sendai, Japan) in 1980. After three years as a postdoctoral fellow at the Department of Pharmacognosy and Pharmacology, College of Pharmacy, University of Illinois at Chicago (UIC) under the supervision of Professor Geoffrey A. Cordell, he joined the Kitasato Institute (Tokyo, Japan) as a senior researcher. After seven years, he joined as a Lecturer and was promoted to Assistant Professor at the Pharmaceutical Institute, Tohoku University. After six years in this position, he joined as an Associate Professor at Aomori University (Aomori, Japan). He was promoted to Professor there, and also served as a Guest Professor at Hirosaki University. After eight years, he became a Professor at Nihon Pharmaceutical University (Saitama, Japan) in 2003 and served as a Department Head for 10 years.

He is the author of about 150 research publications, book chapters, comprehensive reviews, and professional publications; is the author of 11 books, with five more in progress; and is the Associate Editor-in-Chief of the Pharmaceutical Biology (USA). He is a Councilor of the Japanese Society for History of Pharmacy. His interests include the chemistry and biosynthesis of alkaloids, the relationship of poisons and human beings, the Japanese ancient history of Poisons and Medicines, and also the use of vegetables as chemical reagents.

Professor Emeritus Geoffrey A. Cordell obtained his Ph.D. in synthetic natural product chemistry at the University of Manchester in 1970. After two years as a NATO postdoctoral fellow at the Department of Chemistry, M.I.T., he joined the College of Pharmacy, University of Illinois at Chicago (UIC). A Professor since 1980, he served as a Department Head for 12 years and as Interim Dean of the College of Pharmacy for almost three years, as well as holding several other senior academic and research administrative positions at the Department, College, and C