ADP-Ribosylation and Regulation of Cellular Function.- Multiple Aspects of ADP-Ribosylation Reactions.- ADP-Ribosylation as a Cellular Control Mechanism.- Poly(ADP-Ribose): Structure and Enzymology.- Size Distribution of Branched Polymers of ADP-Ribose Generated in Vitro and in Vivo.- Studies on the Structure of Poly(ADP-Ribose) by HPLC. Separation of in Vitro Generated Polymer Chains, Analysis of Chain Length, and Branching.- Probable Helical Conformation of Poly(ADP-Ribose).- Immobilized Poly(ADP-Ribose) Synthetase: Preparation and Properties.- The Domain Structure of Poly(ADP-Ribose) Synthetase and Its Role in Accurate Transcription Initiation.- DNA-Poly(ADP-Ribose) Polymerase Complex: Isolation of the DNA Wrapping the Enzyme Molecule.- The Role of Lysine Residues in the Catalytic Function and DNA Binding of Poly(ADP-Ribose) Polymerase as Determined by the Covalent Modification of the Enzyme Protein with Methyl Acetimidate.- ADP-Ribosyltransferase from Hen Liver Nuclei: Purification, Properties, and Evidence for ADP-Ribosylation-Induced Suppression of Cyclic AMP-Dependent Phosphorylation.- Poly(ADP-Ribosyl)ation of Nuclear Enzymes.- Kinetic Mechanism of Poly(ADP-Ribose) Polymerase.- Specificity of Poly(ADP-Ribose) Synthetase Inhibitors.- Inhibition of ADP-Ribosylation Reaction by 2?,5?-Oligoadenylates.- Activity Gels of Poly(ADP-Ribose) Polymerase: Phylogenetic Studies and Variations in Human Blood Cells.- The Relationship Between DNA Strand Breaks and ADP-Ribosylation.- Mechanism of Ethanol Stimulation of Poly(ADP-Ribose) Synthetase.- Specific Proteolytic Processing of Poly(ADP-Ribose) Polymerase in Human Lymphocytes.- Cytoplasmic Poly(ADP-Ribose) Synthetase in Rat Spermatogenic Cells.- Poly(ADP-Ribose) Polymerase Associated with Cytoplasmic Free mRNP Particles: Effect of RNase A.- Effect of DNA Intercalators on Poly(ADP-Ribose) Glycohydrolase Activity.- 5?-ADP-3?-Deoxypentos-2?-Ulose, a Novel Product of ADP-Ribosyl Protein Lyase.- Glutamyl Ribose-5-Phosphate Storage Disease: Clinical Description and Characterization of the Stored Material.- ADP-Ribosylation and Chromatin Structure.- Effect of Poly(ADP-Ribosyl)ation on Native Polynucleosomes, H1-Depleted Polynucleosomes, Core Particles, and H1-DNA Complexes.- Poly(ADP-Ribose) Glycohydrolase Activity Causes Recondensation of Relaxed Poly(ADP-Ribosyl)ated Polynucleosomes.- Kinetics of Nucleosomal Histone H1 Hyper(ADP-Ribosylation) and Polynucleosomes Relaxation.- DNA Strand-Breaks and Poly(ADP-Ribosylated) Mediation of Transcriptionally Active Chromatin and Transforming Gene Stability.- Poly(ADP-Ribose) in Nucleoids.- ADP-Ribosylation of Nuclear Matrix Proteins. Association of Poly(ADP-Ribose) Synthetase with the Nuclear Matrix.- Psoralen-Probing of Chromatin Organization in Intact Cells Undergoing DNA Excision Repair.- ADP-Ribosylation, DNA Repair, and Chromatin Organization.- ADP-Ribosylation, DNA Repair, and Xenobiotic Stress.- Is There a Role for ADP-Ribosylation in DNA Repair?.- Poly(ADP-Ribosyl)ation, DNA Repair, and Chromatin Structure.- Isolation and Identification of Mono- and Poly(ADP-Ribosyl) Proteins Formed in Intact Cells in Association with DNA Repair.- Mono(ADP-Ribosyl) Histone H1 in Alkylated Hepatoma Cells: Unusual Acceptor Site.- ADP-Ribosylation Reactions in Biological Responses to DNA Damage.- DNA Ligase II of Mammalian Cells.- Isolation of a DNA Ligase Mutant from L1210 Cells.- Environmental Stress and the Regulation of Poly(ADP-Ribose) Metabolism.- Tumor Promoter Phorbol-Myristate-Acetate Induces a Prooxidant State which Causes the Accumulation of Poly(ADP-Ribose) in Fibroblasts.- Kinetic Studies of the ADP-Ribosylation of HSP-83 in Chicken Embryo Fibroblast Cells.- Effects of 3-Aminobenzamide on Cell-Cycle Traverse and Viability of Human Cells Exposed to Agents which Induce DNA Strand-Breakage.- Potentiation of the Effects of Bleomycin and 1,3-Bis(2-Chloroethyl)-1-Nitrosourea on A549 Cell Cultures by Inhibitors of Poly(ADP-Ribose) Synthetase.- Cell Death Caused by the Anti-Cancer Drug Methotrexate: Does ADP-Ribosyl Transferase Have a Role to Play?.- Cytogenetic, Cytotoxic, and Cell-Cycle Effects of 3-Aminobenzamide in Human Lymphoblastoid Cells Proficient or Deficient in Nucleotide Biosynthesis.- Poly(ADP-Ribose) Polymerase Inhibition and the Induction of Mutation in V79 Cells.- Effect of 3-Aminobenzamide on CHO Cells Replicating in Medium Containing Chloro-Deoxyuridine.- Poly(ADP-Ribose) Synthesis in Lymphocytes of Persons Occupationally Exposed to Low Levels of Ionizing Radiation.- ADP-Ribosylation and Cellular Differentiation.- ADP-Ribosyltransferase in Protozoan Differentiation.- ADP-Ribosyltransferase Activity in Trypanosoma brucei.- ADP-Ribose: A Novel Aspect of Steroid Action.- ADP-Ribosylation and Glucocorticoid-Regulated Gene Expression.- Poly(ADP-Ribose) Synthetase and Cell Differentiation.- Interaction of Cyclic AMP and ADP-Ribosylation in a Hormonally Responsive Cell Line.- Poly(ADP-Ribose) Synthetase Inhibitor Effects on Cellular Functions.- Poly(ADP-Ribose) Synthetase Inhibitors Induce Islet B-Cell Regeneration in Partially Depancreatized Rats.- Regulation of Lymphocyte Proliferation by a Continuous Production and Repair of DNA Strand Breaks.- Requirement for ADP-Ribosyltransferase Activity and Rejoining of DNA Strand Breaks During Lymphocyte Stimulation.- Specific Inhibition of the Appearance of a T-Lymphocyte Surface Marker in Thymus Organ Cultures.- Transient Formation of DNA Strand Breaks During DMSO-Induced Differentiation of Promyelocytic Cell Line, HL-60.- Differentiation of a Myoblast Cell Line and Poly(ADP-Ribosyl)ation.- Inhibitors of Poly(ADP-Ribose) Polymerase Prevent Friend Cell Differentiation.- Poly(ADP)-Ribosylation of Nuclear Proteins in the Mouse Testis.- ADP-Ribosylation and Neoplastic Transformation in Vitro and in Vivo.- A Role for Poly(ADP-Ribose) in Radiogenic and Chemically-Induced Malignant Transformation and Mutagenesis.- Effects of 3-Aminobenzamide on the Induction of Toxicity and Transformation by Various Chemicals in BALB/3T3 Cl A 31–1 Cells.- Specific Binding of Benzamide to DNA: Possible Correlation to Antitransforming Activity.- Enhancement by m-Aminobenzamide of Methylazoxymethanol Acetate-Induced Hepatoma of the Small Fish “Medaka” (Oryzias latipes).- Influence of Dietary Nicotinamide on N-Nitrosodimethylamine Carcinogenesis in Rats.- Involvement of Poly(ADP-Ribosylation) Reactions in Liver Carcinogenesis of Diethylnitrosamine in Rats.- Immunofluorescent Staining of Poly(ADP-Ribose) in Situ in Acetone-Fixed HeLa Cells: Its Usefulness for Clinical and Basic Sciences.- Diadenosine Tetraphosphate: A New Target for Cancer Chemotherapy.- Mono(ADP-Ribosylation) Reactions.- Characterization of NAD: Arginine Mono(ADP-Ribosyl)Transferases in Turkey Erythrocytes: Determinants of Substrate Specificity.- Mono(ADP-Ribosyl)ation and Phospho(ADP-Ribosylation)Reactions in Eukaryotic Cells.- Mono(ADP-Ribosylation) of Proteins at Arginine in Vivo.- Calcium Transport and Mono(ADP-Ribosylation) in Mitochondria.- A Cellular Mono(ADP-Ribosyl)Transferase which Modifies the Diphthamide Residue of Elongation Factor-2.- Photochemical Transfer of the Nicotinamide Moiety of NAD to a Specific Residue in the Catalytic Center of Diphtheria Toxin Fragment A.- ADP-Ribosylation of a Membrane Protein Catalyzed by Islet-Activating Protein, Pertussis Toxin.- Why Does Cholera Toxin Need GTP to Act?.- Epilogue.