Addiction Reviews, Volume 1282 Annals of the New York Academy of Sciences Series

The fifth installment of Addiction Reviews provides refereed reviews on learning theory and addition, deep brain stimulation and addiction, novel therapeutic approaches to addiction, developmental studies of reward, genetics and brain imaging in addiction, genetics of alcoholism and its comorbidities, in addition to other state-of-the art topics in addiction science.

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Preface to Addiction Review iv
George R. Uhl

Evaluation of reward from pain relief 1
Edita Navratilova, Jennifer Yanhua Xie, Tamara King and Frank Porreca

Associative learning mechanisms underpinning the transition from recreational drug use to addiction 12 
Lee Hogarth, Bernard W. Balleine, Laura H. Corbit and Simon Killcross

Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse 25 
Emma Leishman, Kevin J. Kokesh and Heather B. Bradshaw

The genetics of alcohol dependence 39 
Marcella Rietschel and Jens Treutlein

Substance use disorders: a theory-driven approach to the integration of genetics and neuroimaging 71 
Hollis C. Karoly, Nicole Harlaar and Kent E. Hutchinson

Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study 92 
Charlotte Nymberg, Tianye Jia, Barbara Ruggeri and Gunter Schumann

Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications 107 
Carlo Contoreggi, Mary R. Lee and George Chrousos

Deep brain stimulation of the nucleus accumbens for the treatment of addiction 119 
Ulf J. Müller, Jürgen Voges, Johann Steiner, Imke Galazky, Hans-Jochen Heinze, Michaela Möller, Jared Pisapia, Casey Halpern, Arthur Caplan, Bernhard Bogerts and Jens Kuhn

George R. Uhl, MD, PhD, Molecular Neurobiology, National Institutes of Health IRP (NIDA).