A genetic switch, (3^rd Ed.)

The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long–range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works.

The Master Elements of Control. Protein–DNA Interactions and Gene Control. Control Circuits–Setting the Switch. How Do We Know–The Key Experiments. 2004: New Developments.