Natural Products Chemistry of Botanical Medicines from Cameroonian Plants Natural Products Chemistry of Global Plants Series

A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure.

Key Features:

• Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources
• Addresses the current development of pharmacognosy research in Cameroon
• Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential
• Covers an extensive range of chemical, botanical and pharmacological diversities

Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.

Contents

Book Series: Natural Products Chemistry of Global Plants.....................................vii

Introduction – Cameroon...........................................................................................ix

Editor........................................................................................................................xi

Contributors............................................................................................................ xiii

Chapter 1 The Genus Olax: Traditional Uses, Phytochemistry

and Biological Activities.......................................................................1

Bienvenu Tsakem, Beaudelaire Kemvoufo Ponou,

Billy Tchegnitegni Toussie, Romuald Fouedjou Tematio,

Xavier Siwe-Noundou, Rui W.M. Krause,

Rémy Bertrand Teponno, and Léon Azefack Tapondjou

Chapter 2 Chemistry and Biological Activities of Cameroonian

Hypericum Species..............................................................................23

Gabin Thierry M. Bitchagno, Vaderament-A

Nchiozem-Ngnitedem, Sylvain Valere Sob, and Serge Alain Fobofou

Chapter 3 Biologically Active Saponins from Some Cameroonian

Medicinal Plants.................................................................................. 37

Léon Azefack Tapondjou, Rémy Bertrand Teponno,

Beaudelaire Kemvoufo Ponou, Romuald Tematio Fouedjou,

and Luciano Barboni

Chapter 4 Antioxidant and Immunomodulatory Activities of Cameroonian

Medicinal Plants..................................................................................83

Matthias Onyebuchi Agbo, Patience O. Osadebe,

Xavier Siwe-Noundou, and Rui W.M. Krause

Chapter 5 Chemometric Evaluation of Phytochemical Principles in

Cameroonian Plants............................................................................99

Ezealisiji Kenneth Maduabuchi

Chapter 6 Medicinal Plants from Cameroon for Obstetric

and Gynecological Uses.................................................................... 123

Bazil Ekuh Ewane, Benjamin C. Ozumba, Patience O. Osadebe,

Philip F. Uzor, and Xavier Siwe-Noundou

vi Contents

Chapter 7 Ondongdong si (Acmella caulirhiza Delile), a Medicinal Plant

from Cameroon................................................................................. 141

Tanyi M. Kima and Eleonora D. Goosen

Chapter 8 Cameroonian Allanblackia Species.................................................. 183

Jean Emmanuel Mbosso Teinkela

Index ...................................................................................................................... 201

Dr. Xavier Siwe-Noundou is a scholar and scientist based at Rhodes University in

Grahamstown / Makhanda, South Africa. He has been a Gordon and Betty Moore

Foundation (GBMF) Fellow (2017-2019), Oregon State University in USA (2017),

University of California San Diego in USA (2019); an EU FP7 Marie Curie Fellow

(2015–2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in

Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa

Fellow (2014-2016).

Dr. Siwe-Noundou works on medicinal chemistry focusing on chemistry, pharmacognosy,

and nanotechnology. His main investigations include terrestrial natural

products chemistry (from Cameroon and South Africa) and marine natural products

chemistry (from South Africa cost line). All the bioactive metabolites isolated are

screened as potential antimicrobial, antiparasitic and antiproliferative candidates. He

is an author of more than fifty scientific publications in his field of expertise.