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Notice

Twenty years of G-SCF: clinical and nonclinical discoveries (Milestones in drug therapy)

Auteurs : MOLINEUX Graham, FOOTE MaryAnn, ARVEDSON Tara L.

179,30 €

Disponible chez l'éditeur (délai d'approvisionnement : 10 jours).

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Date de parution : 11-2011
Langue : Français
Ouvrage 578 p. 15.5x23.5 cm Relié

Résumé de Twenty years of G-SCF: clinical and nonclinical...

Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled progenitor cell transplantation to supplant bone marrow transplantation as a more effective treatment. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and non-oncology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

Sommaire de Twenty years of G-SCF: clinical and nonclinical...

Basic Science.- Use of rHuG-CSF in the Oncology Setting.- Use of rHuG-CSF in Non-Oncology Setting.- Safety and Economics.- The Next 20 Years.