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Clinical Trials Explained A Guide to Clinical Trials in the NHS for Healthcare Professionals

Langue : Anglais

Coordonnateurs : Kerr David J., Knox Kirstine, Robertson Diane, Stewart Derek, Watson Renee

Couverture de l’ouvrage Clinical Trials Explained
Designed in consultation with doctors and patients who have taken part in trials, this work provides a detailed guide to the clinical trials process. It also helps both clinicians and patients make well-informed decisions on whether to take part in a clinical trial.
Chapter 1 Overview and Purpose of this Guide to Clinical Trials in the NHS.

Overview and purpose of this guide.

Who should use this guide to clinical trials in the NHS?.

Chapter 2 Clinical Trials Explained.

What are clinical trials?.

Why are clinical trials needed?.

Who is involved in a clinical trial?.

How are clinical trials designed and approved?.

Progression of a medical intervention through the clinical trial phases.

Summary.

Chapter 3 Clinical Trial Approval, Regulation and Funding.

How are clinical trials approved and regulated?.

Ethical approval.

Informed consent.

How are trials managed?.

Who pays for a clinical trial?.

Summary.

Chapter 4 Understanding Clinical Trial Design and Results.

Understanding randomisation and blinding in clinical trials.

Understanding controls and placebos.

Why are placebos used in clinical trials?.

What about trials that are not controlled or blinded?.

Understanding clinical trial results.

Summary.

Chapter 5 Questions About Clinical Trials: A Framework for Discussion.

What are patients rights?.

Why do patients take part in clinical trials?.

Why do patients decline to take part in a clinical trial or withdraw from a clinical trial they are involved in?.

How can patients be empowered during their involvement in a.

clinical trial?.

Will patients involved in clinical trials need extra help and support from.

their carers?.

What are the likely costs of and reimbursement for patients participating.

in clinical trials?.

Summary.

Appendix A Finding Out About Clinical Trials that are Currently or Soon to be Recruiting.

Appendix B ECRI Evidence Report: Patients Reasons for Participation in Clinical Trials and Effect of Trial Participation on Patient Outcomes.

Glossary.

Index

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