AJCC Cancer Staging Manual (8^th Ed.)

Please visit www.cancerstaging.org for information about content updates and staging forms.

The AJCC Cancer Staging Manual is used by physicians and health care professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging of cancer is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome.

Significantly expanded and developed by international disease site expert panels, the Eighth Edition AJCC Cancer Staging Manual brings together all the currently available knowledge on staging of cancer at various anatomic sites. In this edition, evidence-based TNM staging is supplemented, as appropriate, by selected molecular markers and newly acquired insights into the molecular underpinnings of cancer. This edition features 12 entirely new staging systems, a wide range of changed or new staging definitions, and a refined emphasis on a personalized-medicine approach. To enhance the print and electronic usability of the cancer staging forms, they are now available exclusively for access and downloading at www.cancerstaging.org.

The Eighth Edition AJCC Cancer Staging Manual remains the gold standard reference for oncologists, surgeons, pathologists, radiologists, cancer registrars and medical professionals world-wide to ensure that all those caring for cancer patients are fully versed in the language of cancer staging.

Part I General Information on Cancer Staging and End-Results Reporting.- 1. Principles of Cancer Staging.- . Organization of the AJCC Cancer Staging Manual.- 3. Cancer Survival Analysis.- 4. Risk Models for Individualized Prognosis in the Practice of Precision Oncology.- Part II Head and Neck.- 5. Staging Head and Neck Cancers.- 6. Cervical Lymph Nodes and Unknown Primary Tumors of the Head and Neck.- 7. Lip and Oral Cavity.- 8. Major Salivary Glands.- 9. Nasopharynx.- 10. HPV-Mediated (p16+) Oropharyngeal Cancer.- 11. Oropharynx (p16−) and Hypopharynx.- 12. Nasal Cavity and Paranasal Sinuses.- 13. Larynx.- 14. Mucosal Melanoma of the Head and Neck.- 15. Cutaneous Squamous Cell Carcinoma of the Head and Neck.- Part III Upper Gastrointestinal Tract.- 16. Esophagus and Esophagogastric Junction.- 17. Stomach.- 18. Small Intestine.- Part IV Lower Gastrointestinal Tract.- 19. Appendix – Carcinoma.- 20. Colon and Rectum.- 21. Anus.- Part V Hepatobiliary System.- 22. Liver.- 23. Intrahepatic Bile Ducts.- 24. Gallbladder.- 25. Perihilar Bile Ducts.- 26. Distal Bile Duct.- 27. Ampulla of Vater.- 28. Pancreas – Exocrine.- Part VI Neuroendocrine Tumors.- 29. Neuroendocrine Tumors of the Stomach.- 30. Neuroendocrine Tumors of the Duodenum and Ampulla of Vater.- 31. Neuroendocrine Tumors of the Jejunum and Ileum.- 32. Neuroendocrine Tumors of the Appendix.- 33. Neuroendocrine Tumors of the Colon and Rectum.- 34. Neuroendocrine Tumors of the Pancreas.- Part VII Thorax.- 35. Thymus.- 36. Lung.- 37. Malignant Pleural Mesothelioma.- Part VIII.- Bone.- 38. Bone (appendicular skeleton, spine, and pelvis).- Part IX Soft Tissue Sarcoma.- 39. Introduction.- 40. Soft Tissue Sarcoma of the Head and Neck.- 41. Soft Tissue Sarcoma of the Trunk and Extremities.- 42. Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs.- 43. Gastrointestinal Stromal Tumor.- 44. Soft Tissue Sarcoma of the Retroperitoneum.- 45. Soft Tissue Sarcoma – Unusual Histologies and Sites.- Part X Skin.- 46. Merkel Cell Carcinoma.- 47. Melanoma of the Skin.- Part XI Breast.- 48. Breast.- Part XII Female Reproductive Organs.- 49. Introduction.- 50. Vulva.- 51. Vagina.- 52. Cervix Uteri.- 53. Corpus Uteri – Carcinoma and Carcinosarcoma.- 54. Corpus Uteri – Sarcoma.- 55. Ovary, Fallopian Tube, and Primary Peritoneal Carcinoma.- 56. Gestational Trophoblastic Neoplasms.- Part XIII Male Genital Organs.- 57. Penis.- 58. Prostate.- 59. Testis.- Part XIV Urinary Tract.- 60. Kidney.- 61. Renal Pelvis and Ureter.- 62. Urinary Bladder.- 63. Urethra.- Part XV Ophthalmic Sites.- 64. Eyelid Carcinoma.- 65. Conjunctival Carcinoma.- 66. Conjunctival Melanoma.- 67. Uveal Melanoma.- 68. Retinoblastoma.- 69. Lacrimal Gland Carcinoma.- 70. Orbital Sarcoma.- 71. Ocular Adnexal Lymphoma.- Part XVI Central Nervous System.- 72. Brain and Spinal Cord.- Part XVII Endocrine System.- 73. Thyroid – Differentiated and Anaplastic Carcinoma.- 74. Thyroid – Medullary Carcinoma.- 75. Parathyroid.- 76.Adrenal Cortical Carcinoma.- 77. Adrenal – Neuroendocrine Tumors.- Part XVIII Hematologic Malignancies.- 78. Introduction.- 79. Hodgkin and Non-Hodgkin Lymphomas.- 80. Pediatric Hodgkin and Non-Hodgkin Lymphomas.- 81. Primary Cutaneous Lymphomas.- 82. Multiple Myeloma and Plasma Cell Disorders.- 83. Leukemia.- Part XIX Additional Contributors.- Index.