PAKs, RAC/CDC42 (p21)-activated Kinases Towards the Cure of Cancer and Other PAK-dependent Diseases
Coordonnateur : Maruta Hiroshi
1. Functional Maturation of PAKs2. Oncogenicity of PAKs and Their Substrates3. Natural or Synthetic Therapeutics that Block PAKs4. PAK1 in Parasites-Host Interaction5. PAK1 in Brain Diseases6. PAK1 in Alzheimer’s and Huntington’s diseases7. PAK1 Controls the Lifespan8. PAK 4-6 in Cancer and Neuronal Development
- This publication will be the very first book ever published solely focused on PAK family kinases
- Each chapter deals with the latest progress in PAK research written by a leading PAK expert with his or her own ideas and insight
- Each chapter of this book has been written in such a way that clinical doctors who seek the effective cure of these formidable diseases, in addition to research scientists and biomedical students will value this book
- This book describes in detail a number of PAK blockers which would be potentially useful for the therapy of these PAK-dependent diseases, and some of them are indeed available on the market inexpensively, without any side effect
Date de parution : 02-2013
Ouvrage de 276 p.
15x22.8 cm
Épuisé
Mots-clés :
ß-catenin; AIDS; AMPK; Alzheimer's disease; Angiogenesis; Antimalaria drugs; Artepillin C; Autoinhibitory domain; BAD; Bio 30; Blood-brain barrier; Breast cancer; C-terminus; CAPE; CDC42; CRIB; Calorie restriction; Cancer; Colon cancer; Curcumin; Depression; ERK; Epilepsy; EspG; Estrogen receptor; FK228; FOXO; Flu; Fragile X syndrome; GTPases; Glioma; H pylori; HIV; HPV; HSP16; Huntington's disease; Influenza virus; Inhibitory switch domain; LD; LIM kinase; LKB1; Malaria; Mental retardation; Merlin; Metastasis; Multicellular; N-terminus; NF; Neurofibromatosis; PAK; PAK1-3 kinase; PAKs; Pancreatic cancer; Propolis; Protein kinase; RAC; RAF; RAS; RB; S6K; Schizophrenia; Synapses; TOR; TSC; Tuberous sclerosis; Unicellular