LC-MS in Drug Bioanalysis, 2012
Coordonnateurs : Xu Q. Alan, Madden Timothy L.
Internal standards for quantitative LC-MS bioanalysis.- Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS.- Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry.- Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry.- Pitfalls of LC-MS/MS in the clinical laboratory.- Therapeutic drug monitoring to support clinical pharmacogenomics.- Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices.- The analysis of antipsychotic drugs in human biosamples by LC-MS.- Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective.- Applications of mass spectrometry in analyses of steroid hormones.- Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications.- Analysis of illicit drugs in human biological samples by LC-MSn.- Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs.- A planar integrated micro mass spectrometer.
Date de parution : 08-2014
Ouvrage de 472 p.
15.5x23.5 cm
Date de parution : 07-2012
Ouvrage de 472 p.
15.5x23.5 cm
Thèmes de LC-MS in Drug Bioanalysis :
Mots-clés :
Bioanalysis; LC-MS; LC-MS/MS; Liquid chromatography; MS; anticancer drugs; antidementia drugs; antidepressants; antiepileptic drugs; antifundal drugs; antimicrobial drugs; antipsychotic drugs; antiretroviral Drugs; anxiolytic/hypnotic drugs; cardiac drugs; drugs for addiction; immunosuppressants; mass spectrometry; metabolites; mood stabilizers