Ion Channels Down Under

Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and their role in a diverse range of poorly treated medical conditions. This new volume covers specific topics relating to Receptors and the Diversity in their Structure and Pharmacology, Acid-Sensing Ion Channel Pharmacology, Past, Present and Future, Sodium Channels and Venom Peptide Pharmacology, the Role of Non-Neuronal TRPV4 Signaling in Inflammatory Processes, and Genetically Encoded Calcium Indicators as Probes to Assess the Role of Calcium Channels in Disease and for High-Throughput Drug Discovery.

Contributors in this series include prominent scientists and highly-recognized experts with major accomplishments in the field of ion channel pharmacology. Topics covered include the role of ion channels in health and disease, ion channels as therapeutic targets and the molecular pharmacology of ion channels.

1. GABA_A Receptors and the Diversity in their Structure and Pharmacology Han Chow Chua and Mary Chebib 2. Acid-Sensing Ion Channel Pharmacology, Past, Present and Future… Lachlan D. Rash 3. Sodium Channels and Venom Peptide Pharmacology Mathilde Israel, Bryan Tay, Jennifer Deuis and Irina Vetter 4. Role of Non-Neuronal TRPV4 Signaling in Inflammatory Processes Pradeep Rajasekhar, Daniel P. Poole and Nicholas A. Veldhuis 5. Genetically Encoded Calcium Indicators as Probes to Assess the Role of Calcium Channels in Disease and for High-Throughput Drug Discovery John J. Bassett and Gregory R. Monteith 6. TRPV1 Channels in Immune Cells and Hematological Malignancies Sofia Omari, Murray Adams and Dominic Geraghty 7. Modulation of Ion Channels by Cysteine-Rich Peptides: From Sequence to Structure Mehdi Mobli, Eivind A.B. Undheim and Lachlan D. Rash 8. Glycine Receptor Drug Discovery Joseph W. Lynch, Yan Zhang, Sahil Talwar and Argel Estrada-Mondragon 9. Voltage-Gated Sodium Channel Pharmacology - Insights from Molecular Dynamics Simulations Rong Chen, Amanda Buyan and Ben Corry 10. Physiology and Pharmacology of Ryanodine Receptor Calcium Release Channels Angela F. Dulhunty, Philip G. Board, Nicole A. Beard and Marco G. Casarotto

• Provides a must read book on ion channel pharmacology
• Contains up-to-date information on a number of ion channels, their pharmacological modulators, and their role in a diverse range of poorly treated medical conditions
• Contains contributions from prominent scientists and highly-recognized experts with major accomplishments in the field