Drug Discovery From Bedside to Wall Street

Langue : Anglais

Auteurs : Bartfai Tamas, Lees Graham V.

Résumé
Sommaire
Lectorat
Biographie
Commentaire

Everyone expects something from the drug industry. Physicians and patients, investors, regulators and administrators all have an active interest. Everyone wants to know what makes drugs ?work? medically and economically. Why are drugs so expensive? Is it the drug companies or investors who demand high profits? What governs the pharmacoeconomics? Why are so few diseases treatable?

Drug Discovery opens the windows and doors of the industry telling the story of drug development by using real stories from inside the process.

Section Headings:
Introduction
Part I. Medicine for Society
Part II. From Basics to Bedside
Part III. The Business of Making & Selling Legal Drugs
Part IV. What Will Matter in Making Medicines?

Academics/Scientists interested in working with biotech and pharma companies

Tamas Bartfai was a student of mathematics, physics, and chemistry before translating his skills into biochemistry, pharmacology and neuroscience. Trained in Stockholm University, Yale University, and The Rockefeller University, he is presently a professor at The Scripps Research Institute, the University Oxford, and the University of Pennsylvania, and an expert in medicinal chemistry and the neurological sciences. He has been working in the development of new medicines and vaccines for many years as a former Sr.VP of Hoffmann La Roche, and long-term consultant at Astra, Novartis and, presently, Pfizer. Eight of the drugs Dr. Bartfai developed are in clinical use and three are in trials. He has trained and collaborated with many scientists throughout his scientific work on the topics of fever, neuropeptides, and prostaglandins, while publishing over 400 articles in over 80 journals.

Dr. Bartfai has held many prestigious academic positions. He is a member of Academia Europae and the Hungarian Academy of Sciences, a fellow of AAAS for pioneering work on neuropeptides, and a member of the Royal Swedish Academy of Sciences, which awards the Nobel Prizes in Chemistry and Physics. He was professor of the Karolinska Institute, which awards the Nobel Prize in Medicine or Physiology. He has been awarded a number of prestigious prizes including Eötvös Medal for mathematics in 1966, Budapest, Hungary; Royal Swedish Academy’s Svedberg Prize for biochemistry in 1985 and Ericsson Prize in 1996; and the Ellison Medical Foundation Senior Scholar Award 2002.
Graham V Lees acquired his BA, MA and PhD degrees at the University of Cambridge. His postdoctoral work on the biophysics of ion channels was followed by a lengthy career in scientific, technical and medical publishing with Elsevier (Amsterdam), Raven Press (New York), Academic Press (San Diego & London) and TheScientificWorld (San Diego, Boynton Beach, Newbury & Helsinki). His scientific writing has been actively incr

Co-written by Graham Lees and Tamas Bartfai who has been involved in the development of drugs taken by more that 20 million people every day
Opens the windows and doors of the most regulated industry in the world, the pharmaceutical industry
Tells the story of drug development by using real examples based on current research and events
Provides an objective, lucid account of the successes and failures, shortcomings and constraints of the pharmaceutical and biotech industries
Gives insights into the development of new drugs to combat multiple conditions including cancer and pain
Balanced, unbiased account of how better to translate basic science into drug discovery